Lin Chen
5 Papers
Lin Chen is an academic researcher. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 3, co-authored 3 publications.
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Papers
An anti-inflammatory and neuroprotective biomimetic nanoplatform for repairing spinal cord injury
Xiang Gao,Z A Han,Sheng Huang,Huali Lei,Guangqiang Li,Lin Chen,Dandan Feng,Zijie Zhou,Qin Shi,Liang Cheng,Xiaozhong Zhou +10 more
TL;DR: Wang et al. as mentioned in this paper used bovine serum albumin (BSA) self-assembly to obtain [email protected]@Cur nanoparticles (NPs) for spinal cord regeneration after a spinal cord injury.
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Multifunctional Supramolecular Filament Hydrogel Boosts Anti‐Inflammatory Efficacy In Vitro and In Vivo
Jie Deng,Deqing Lin,Xiangyun Ding,Yuanzhong Wang,Yuhan Hu,Hui Shi,Lin Chen,Bingyang Chu,Lei Lei,Chunmei Wen,Jiaqing Wang,Zhiyong Qian,Xingyi Li +12 more
TL;DR: New insights are offered into the anti‐inflammatory mechanism of PDCs hydrogel and presents the therapeutic values in the treatment of ocular disorders, and ultimately fulfils the potential clinical benefits of P DCs.
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Enzyme-instructed self-assembly of peptide-drug conjugates in tear fluids for ocular drug delivery.
Yuhan Hu,Yuan Wang,Jie Deng,Xiangyun Ding,Deqing Lin,Hui Shi,Lin Chen,Dan Lin,Yuqin Wang,Serhii Vakal,Jiaqing Wang,Xingyi Li +11 more
TL;DR: In this article , an enzyme-instructed self-assembly (EISA) strategy was used to design a peptide-drug (IBF-HYD-GFFpY) precursor through the ester bond to release active drugs at the target site.
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Supramolecular nanofiber of indomethacin derivative confers highly cyclooxygenase-2 (COX-2) selectivity and boosts anti-inflammatory efficacy.
Deqing Lin,Xiaoning Xu,Lin Chen,Lei Chen,Mengyun Deng,Jinrun Chen,Zhibin Ren,Lei Lei,Jiaqing Wang,Jie Deng,Xingyi Li +10 more
TL;DR: A simple method for converting non-selective nonsteriodal anti-inflammatory drugs (NSAIDs) into highly selective COX-2 inhibitors that can self-assemble into supramolecular hydrogel for anti-inflammation applications is presented.
Collagen membrane functionalized with magnesium oxide via room-temperature atomic layer deposition promotes osteopromotive and antimicrobial properties
Soumya Saha,Raphael Cavalcante Costa,Mirela Caroline Silva,João Matheus Fonseca-Santos,Lin Chen,Abhijit H. Phakatkar,Harshdeep Bhatia,Leonardo Perez Faverani,Valentim Adelino Ricardo Barão,Tolou Shokuhfar,Cortino Sukotjo,Christos G. Takoudis +11 more
TL;DR: In vivo studies performed on calvaria rats showed MgO-coated membranes elicit a higher inflammatory response, leading to an increase in angiogenesis and a greater bone formation, mainly for Col-MgO500, compared to uncoated collagen.