Lin Chen
10 Papers
5 Citations
Lin Chen is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 8 publications.
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Papers
Bone marrow mesenchymal stem cells enhance angiogenesis and promote fat retention in fat grafting via polarized macrophages
Juanli Dang,Jizhong Yang,Zhou Yu,Lin Chen,Zhaoxiang Zhang,Kai Wang,Jiezhang Tang,Chenggang Yi +7 more
TL;DR: Wang et al. as discussed by the authors found that BM-MSCs improved retention by enhancing angiogenesis in fat grafting, which may be related to M2 macrophage polarization in vitro.
Revealing the roles of glycosphingolipid metabolism pathway in the development of keloid: a conjoint analysis of single-cell and machine learning
Binyu Song,Yunxia Zheng,Hao Chi,Yuhan Zhu,Zhiwei Cui,Lin Chen,Guo Chen,Botao Gao,Yichen Du,Zhou Yu,Baoqiang Song +10 more
TL;DR: In this article , the role of the glycosphingolipid (GSL) metabolism pathway in the development of keloid was investigated, and it was shown that the increased activity of the GSL metabolism pathway was associated with fibroblast differentiation.
Deciphering the contributions of cuproptosis in the development of hypertrophic scar using single-cell analysis and machine learning techniques
Binyu Song,Wei Liu,Yuhan Zhu,Yixuan Peng,Zhiwei Cui,Botao Gao,Lin Chen,Zhou Yu,Baoqiang Song +8 more
TL;DR: Wang et al. as discussed by the authors used single-cell sequencing and bulk transcriptome data, and screened for cuproptosis-related genes (CRGs) using differential gene analysis and machine learning algorithms (random forest and support vector machine).
Larp6 regulates keloid fibroblasts proliferation, invasion and collagen synthesis.
TL;DR: In this paper , the authors performed immunohistochemistry staining on human keloid tissues and discovered markedly upregulated LARP6 expression in lesion fibroblasts compared with that of normal skin and hypertrophic scar tissues.
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EGCG inhibits hypertrophic scar formation in a rabbit ear model
Yajuan Song,Tong Wang,Liuqing Yang,Junzheng Wu,Lin Chen,Xiaoqin Fan,Zhe Zhang,Qing Yang,Zhou Yu,Baoqiang Song +9 more
TL;DR: In this article , the therapeutic effects of EGCG on hypertrophic scar were analyzed using a rabbit ear hypertrophic Scar model, and the results showed that EGCGs improved wound healing and tissue fibrosis in both rats and mice.
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