Lilly Yuen
Royal Melbourne Hospital
15 Papers
63 Citations
Lilly Yuen is an academic researcher from Royal Melbourne Hospital. The author has contributed to research in topics: Hepatitis B virus & Hepatitis B. The author has an hindex of 8, co-authored 15 publications.
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Papers
Circulation of Type 1 Vaccine-Derived Poliovirus in the Philippines in 2001
Hiroyuki Shimizu,Bruce R Thorley,Fem Julia E. Paladin,Kerri Anne Brussen,Vicki Stambos,Lilly Yuen,Andi Utama,Yoshio Tano,Minetaro Arita,Hiromu Yoshida,Tetsuo Yoneyama,Agnes Benegas,Sigrun Roesel,Mark A. Pallansch,Olen M. Kew,Tatsuo Miyamura +15 more
TL;DR: In 2001, highly evolved type 1 circulating vaccine-derived poliovirus (cVDPV) was isolated from three acute flaccid paralysis patients and one contact from three separate communities in the Philippines as mentioned in this paper.
157
The evolution and clinical impact of hepatitis B virus genome diversity
Peter Revill,Peter Revill,Thomas Tu,Thomas Tu,Hans J Netter,Lilly Yuen,Stephen Locarnini,Margaret Littlejohn,Margaret Littlejohn +8 more
TL;DR: HBV seems to undergo very little long-term mutational variation despite multiple host–virus factors driving short-term viral variations, which must be considered in the development of new therapeutic regimens.
140
Deep sequencing shows that HBV basal core promoter and precore variants reduce the likelihood of HBsAg loss following tenofovir disoproxil fumarate therapy in HBeAg-positive chronic hepatitis B
Julianne Bayliss,Lilly Yuen,Gillian Rosenberg,Darren Wong,Darren Wong,Margaret Littlejohn,Kathleen Jackson,Anuj Gaggar,Kathryn M. Kitrinos,G. Mani Subramanian,Patrick Marcellin,Maria Buti,Harry L.A. Janssen,Edward Gane,Vitina Sozzi,Danni Colledge,R. Hammond,Rosalind Edwards,Stephen Locarnini,Alexander J. Thompson,Peter Revill +20 more
TL;DR: Patients with detectable BCP and/or PC variants and higher viral diversity have a lower probability of HBsAg loss during long-term NA therapy, and strategies to achieve functional cure of HBV infection should consider using NGS to stratify patients according to BCP/PC sequence.
58
Chronic hepatitis B: recommendations for therapy based on the natural history of disease in Australian patients
Sally Bell,A. Lau,Alexander J. Thompson,Katrina J R Watson,B. Demediuk,Gideon Shaw,Robert Y M Chen,Anna Ayres,Lilly Yuen,Angeline Ingrid Bartholomeusz,Stephen Locarnini,Paul V. Desmond +11 more
TL;DR: Two thirds of this cohort had active replication and were at increased risk of developing cirrhosis and/or hepatoma, and Screening should be offered to people born in, or with parents born in areas of high endemnicity.
34
Origins and Evolution of the Primate Hepatitis B Virus.
TL;DR: A model for the origin and evolution of hepatitis B virus (HBV) was proposed in this article, which includes multiple cross-species transmissions and favors subsequent recombination events that result in a pathogen and can successfully transmit and cause persistent infection in the primate host.