Lili Li
Zhejiang University
9 Papers
20 Citations
Lili Li is an academic researcher from Zhejiang University. The author has contributed to research in topics: Breast cancer & Neutrophil extracellular traps. The author has an hindex of 5, co-authored 9 publications.
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Papers
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
Yunben Yang,Lili Li,Chunjing Xu,Yunke Wang,Zhen Wang,Mengyao Chen,Zhou Jiang,Jun Pan,Chenghui Yang,Xiaoqian Li,Kai Song,Junfeng Yan,Wanglan Xie,Xianguo Wu,Zhigang Chen,Ying Yuan,Shu Zheng,Jun Yan,Jian Huang,Fuming Qiu +19 more
TL;DR: The gut microbiota uses LPS as a trigger to regulate MLM accumulation in a chemokine-dependent manner and generate a precancerous inflammatory milieu to facilitate tumourigenesis.
Tumor-derived HMGB1 induces CD62Ldim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer.
Zhen Wang,Chenghui Yang,Lili Li,Xiaoyan Jin,Zhigang Zhang,Haiyan Zheng,Jun Pan,Liyun Shi,Zhou Jiang,Ke Su,Baizhou Li,Xuan Shao,Fuming Qiu,Jun Yan,Jian Huang +14 more
- 17 Sep 2020
TL;DR: The results suggest that the combination of HMGB1 and CD62Ldim neutrophils is a potential marker for breast cancer lung metastasis and is novel target for future prevention and therapy.
Aged neutrophils form mitochondria-dependent vital NETs to promote breast cancer lung metastasis.
Chenghui Yang,Zhen Wang,Lili Li,Zhigang Zhang,Xiaoyan Jin,Pin Wu,Shanshan Sun,Jun Pan,Ke Su,Fang Jia,Leyi Zhang,Haijun Wang,Xiuyan Yu,Xuan Shao,Ke Wang,Fuming Qiu,Jun Yan,Jian Huang +17 more
TL;DR: In this paper, tumor-associated aged neutrophils (Naged, CXCR4+CD62Llow) were found to form neutrophil extracellular traps (NETs) and promote tumor metastasis in patients and mice.
γδ T Cells: Crosstalk Between Microbiota, Chronic Inflammation, and Colorectal Cancer.
TL;DR: Understanding the crucial role of γδ T cells would enable us to manipulate these cells during the CRC sequence and improve the efficacy of tumor therapy.
Androgen Receptor in Breast Cancer: From Bench to Bedside.
TL;DR: The roles of AR in different BC subtypes and AR-targeting therapies based on preclinical and clinical studies are summarized and the possible efficacy of a combination therapy via exploiting the AR-related mechanisms and the research on therapeutic resistance is highlighted.