Lijun Wang
Chinese Academy of Sciences
22 Papers
99 Citations
Lijun Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Insulin receptor & Mesoporous material. The author has an hindex of 12, co-authored 22 publications.
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Papers
Overcoming multidrug resistance of cancer cells by direct intranuclear drug delivery using TAT-conjugated mesoporous silica nanoparticles.
TL;DR: With the nuclear drug delivery fashion, DOX-MSNs-TAT presents a promising strategy in overcoming MDR in cancer cells and improving the therapeutic index of currently available chemotherapeutics by enhancing therapeutic efficacy and reducing side effects.
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A Gd-doped Mg-Al-LDH/Au nanocomposite for CT/MR bimodal imagings and simultaneous drug delivery.
Lijun Wang,Huaiyong Xing,Shengjian Zhang,Qingguo Ren,Limin Pan,Kun Zhang,Wenbo Bu,Xiangpeng Zheng,Liangping Zhou,Weijun Peng,Yanqing Hua,Jianlin Shi +11 more
TL;DR: The synthetic nanocomposite is expected to be a potential theranostic agent for bimodal imagings of cancers and anti-cancer drug delivery as well.
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A facile in situ hydrophobic layer protected selective etching strategy for the synchronous synthesis/modification of hollow or rattle-type silica nanoconstructs
Kun Zhang,Hangrong Chen,Yuanyi Zheng,Yu Chen,Ming Ma,Xia Wang,Lijun Wang,Deping Zeng,Jianlin Shi +8 more
TL;DR: In this article, a general in situ hydrophobic shell-protected selective etching strategy has been developed to synchronously synthesize and modify hollow mesoporous silica nanoparticles (HMSNs) and rattle-type mesoporus silica nanarticles (RMSNs), effectively avoiding the drawbacks of postmodification.
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Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells
Ning Wu,Jia Liu,Xiangzhong Zhao,Zhiyong Yan,Bo Jiang,Lijun Wang,Shousong Cao,Dayong Shi,Xiukun Lin +8 more
TL;DR: Evidence is provided that cardamonin is a novel inhibitor of STAT3 and has the potential to be developed as a new anticancer agent targeting GSCs, and that targeting STAT3 signal pathway is an important strategy for the treatment of human GBM.
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A review of the components of brown seaweeds as potential candidates in cancer therapy
TL;DR: This review will reveal the active components of brown algae, together with their antitumor potential toward cancer treatment according to their structure, to provide useful information for medicinal chemists in their attempts to develop potent anticancer agents.
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