Liani Devito
King's College London
20 Papers
131 Citations
Liani Devito is an academic researcher from King's College London. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 9, co-authored 17 publications.
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Papers
Self-organization of the human embryo in the absence of maternal tissues
Marta N. Shahbazi,Agnieszka Jedrusik,Sanna Vuoristo,Gaëlle Recher,Gaëlle Recher,Anna Hupalowska,Virginia N. Bolton,Norah M. E. Fogarty,Alison Campbell,Liani Devito,Dusko Ilic,Yakoub Khalaf,Kathy K. Niakan,Simon Fishel,Magdalena Zernicka-Goetz +14 more
TL;DR: Using human embryos and human pluripotent stem cells, it is shown that the reorganization of the embryonic lineage is mediated by cellular polarization leading to cavity formation, indicating that the critical remodelling events at this stage of human development are embryo-autonomous.
Pluripotent state transitions coordinate morphogenesis in mouse and human embryos
Marta N. Shahbazi,Antonio Scialdone,Natalia Skorupska,Antonia Weberling,Gaëlle Recher,Meng Zhu,Agnieszka Jedrusik,Liani Devito,Laila Noli,Iain C. Macaulay,Christa Buecker,Y. Khalaf,Dusko Ilic,Thierry Voet,Thierry Voet,John C. Marioni,John C. Marioni,John C. Marioni,Magdalena Zernicka-Goetz +18 more
TL;DR: It is shown that exit from an unrestricted naive pluripotent state is required for epiblast epithelialization and generation of the pro-amniotic cavity in mouse embryos and the relevance of transitions between these states during development of the mammalian embryo is shown.
Self-Organization of the Human Embryo in the Absence of Maternal Tissues
Marta N. Shahbazi,Agnieszka Jedrusik,Sanna Vuoristo,Gaëlle Recher,Gaëlle Recher,Anna Hupalowska,Virginia N. Bolton,Norah M. E. Fogarty,Alison Campbell,Liani Devito,Dusko Ilic,Yakoub Khalaf,Kathy K. Niakan,Simon Fishel,Magdalena Zernicka-Goetz +14 more
TL;DR: It is found that the critical remodeling events during early human postimplantation development are embryoautonomous, highlighting the remarkable and unanticipated self-organizing capacity of the human embryo that has never been witnessed before.
3D In Vitro Model of a Functional Epidermal Permeability Barrier from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
Anastasia Petrova,Anna Celli,Laureen Jacquet,Dimitra Dafou,Debra Crumrine,Melanie Hupe,Matthew Arno,Carl Hobbs,Aleksandra Cvoro,Panagiotis Karagiannis,Liani Devito,Richard Sun,Lillian C. Adame,Robert Vaughan,John A. McGrath,Theodora M. Mauro,Dusko Ilic +16 more
TL;DR: The generation of human epidermal equivalents (HEEs) from human embryonic stem cells and induced pluripotent stem cells are demonstrated, which are structurally similar to native epidermis, with a functional permeability barrier.
113
Wharton's jelly mesenchymal stromal/stem cells derived under chemically defined animal product-free low oxygen conditions are rich in MSCA-1(+) subpopulation.
Liani Devito,Heba Badraiq,Antonio Galleu,Dheraj K. Taheem,Stefano Codognotto,Richard C.M. Siow,Yacoub Khalaf,Annette Briley,Andrew Shennan,Lucilla Poston,John A. McGrath,Eileen Gentleman,Francesco Dazzi,Dusko Ilic +13 more
TL;DR: Easy accessibility, abundance and genetic 'naivety' make WJ MSCs logistically a more attractive source for clinical applications than BM MSCing, and they display antiproliferative activity similar to clinical-grade BM M SCs.
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