Liangchun Wang
University of Minnesota
14 Papers
15 Citations
Liangchun Wang is an academic researcher from University of Minnesota. The author has contributed to research in topics: Medicine & Langerin. The author has an hindex of 5, co-authored 5 publications. Previous affiliations of Liangchun Wang include Sun Yat-sen University.
Chat about Author
Papers
Cholera toxin activates nonconventional adjuvant pathways that induce protective CD8 T-cell responses after epicutaneous vaccination
Irlanda Olvera-Gomez,Sara E. Hamilton,Zhengguo Xiao,Zhengguo Xiao,Carla P. Guimaraes,Hidde L. Ploegh,Kristin A. Hogquist,Liangchun Wang,Liangchun Wang,Stephen C. Jameson +9 more
TL;DR: It is reported that cholera toxin (CT) is superior to other adjuvants in its ability to prime memory CD8 T cells that control bacterial and viral challenges.
34
Conditioning of Langerhans cells induced by a primary CD8 T cell response to self-antigen in vivo.
TL;DR: This study suggests that conditioning of dendritic cells may play a role in maintaining unresponsiveness to self-Ag during chronic inflammation.
15
Enhanced Migratory Ability of Neutrophils Toward Epidermis Contributes to the Development of Psoriasis via Crosstalk With Keratinocytes by Releasing IL-17A
Xiuting Liu,Zhenrui Shi,Sijing Lu,Daniel S. Hong,Xiaoyuan Qiu,Guo-zhen Tan,Hui Xiong,Qing Guo,Liangchun Wang +8 more
TL;DR: It is found that blood neutrophils were increased in psoriasis patients, positively correlated with disease severity and highly expressed CD66b, but not CD11b and CD62L compared to healthy controls, providing a proof-of-concept that development of new drugs targeting migration of neutrophil could be a more specific and safe solution to treat Psoriasis.
Topical histone deacetylase 1 inhibitor Entinostat ameliorates psoriasiform dermatitis through suppression of IL-17A response.
TL;DR: Wang et al. as mentioned in this paper investigated the role of topical Entinostat, a selective inhibitor of histone deacetylases 1 (HDAC1) that has been tested in clinic trials to treat solid tumors and hematological malignancies, in psoriasis therapy.
7
Profiling Serum Cytokines and Anticytokine Antibodies in Psoriasis Patients
Dan Hong,Xiuting Liu,Xiaonan Qiu,Siyao Lu,Yanyun Jiang,Guo-zhen Tan,Zhenrui Shi,Liangchun Wang +7 more
TL;DR: The finding suggested that the levels of circulating bioactive IL-17A were associated with disease activity in psoriasis patients and the titers of ACAAs were not significantly altered nor correlated with disease severity, however, the functionality ofACAAs remains to be further demonstrated in vitro in future studies.