Liang Chen
Anhui Medical University
27 Papers
8 Citations
Liang Chen is an academic researcher from Anhui Medical University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 6 publications.
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Papers
A Necroptosis-Related Prognostic Model of Uveal Melanoma Was Constructed by Single-Cell Sequencing Analysis and Weighted Co-Expression Network Analysis Based on Public Databases
Jiaheng Xie,Liang Chen,Q. Tang,Wei Wei,Yuan Cao,Chuyan Wu,Jing Hang,Kai Zhang,Jin-Tao Shi,Ming Wang +9 more
TL;DR: By necroptosis-related prognostic model, UVM patients in both TCGA and GEO cohorts could be classified as high- NCPS and low-NCPS groups, with significant differences in survival time between the two groups (P<0.001), suggesting that they might be more likely to benefit from immunotherapy.
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A necroptosis related prognostic model of pancreatic cancer based on single cell sequencing analysis and transcriptome analysis
Liang Chen,Xueming Zhang,Qixiang Zhang,Tao Zhang,Jiaheng Xie,Wei Wei,Ying Wang,Hongzhu Yu,Hong-Kun Zhou +8 more
TL;DR: The necroptosis-related signature in pancreatic cancer is constructed using single-cell sequencing analysis and transcriptome analysis and can provide a reference for the diagnosis, treatment and prognosis assessment of Pancreatic cancer.
Pan-cancer analysis and single-cell analysis revealed the role of ABCC5 transporter in hepatocellular carcinoma.
TL;DR: Wang et al. as discussed by the authors found that the expression of ABCC5 was upregulated in HCC and was associated with poor prognosis, however, the exact mechanism of the up-regulated expression was not explored.
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Clinical Significance and Potential Role of LSM4 Overexpression in Hepatocellular Carcinoma: An Integrated Analysis Based on Multiple Databases
Liang Chen,Yunhua Lin,Guo-qing Liu,Jingjing Huang,Wei Wei,Zhonghua Yang,Yiming Hu,Jiaheng Xie,Hongzhu Yu +8 more
TL;DR: Overexpressed LSM4 may serve as a promising diagnostic and prognostic biomarker of H CC and may play a synergistic effect with CEGs in promoting the growth and metastasis of HCC cells via regulating crucial pathways such as cell cycle, focal adhesion, and metabolism-associated pathways.
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Construction and validation of the diagnostic model of keloid based on weighted gene co-expression network analysis (WGCNA) and differential expression analysis
Jiaheng Xie,Xiong Zhang,Kai Zhang,Chuyan Wu,Gang Yao,Jing-ping Shi,Liang Chen,Yiming Hu,Dan Wu,Guoyong Yin,Ming Wang +10 more
TL;DR: This study identified seven genes with significant differences in keloids through weighted gene co-expression network analysis (WGCNA) and differential expression analysis and constructed a keloid diagnostic model using five of these genes.
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