Li Yan
University of Macau
30 Papers
98 Citations
Li Yan is an academic researcher from University of Macau. The author has contributed to research in topics: Mesenchymal stem cell & Biology. The author has an hindex of 12, co-authored 28 publications. Previous affiliations of Li Yan include China Agricultural University & University of Minnesota.
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Papers
Concise Review: Mesenchymal Stem Cells Derived from Human Pluripotent Cells, an Unlimited and Quality-Controllable Source for Therapeutic Applications.
TL;DR: A review of mesenchymal stem cells (MSCs) can be found in this article, which summarizes the progress on ps-MSCs and discusses perspectives and challenges for their potential translation to the clinic.
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Critical Role of Tumor Necrosis Factor Signaling in Mesenchymal Stem Cell-Based Therapy for Autoimmune and Inflammatory Diseases.
Li Yan,Dejin Zheng,Ren-He Xu +2 more
TL;DR: This review will introduce the fascinating progress in this aspect of research and discuss remaining questions and future perspectives of Mesenchymal stem cells as a therapy for autoimmune disease.
Spheroidal formation preserves human stem cells for prolonged time under ambient conditions for facile storage and transportation.
TL;DR: This work offers an alternative and relatively simple method termed spheropreservation versus the conventional method cryopreservation that shall remarkably simplify long-distance transportation of stem cells of these and probably also other types within temperature-mild areas, and facilitate therapeutic application of MSC as spheroids without further processing.
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Transplantation of human ESC-derived mesenchymal stem cell spheroids ameliorates spontaneous osteoarthritis in rhesus macaques.
Bin Jiang,Xufeng Fu,Li Yan,Shanshan Li,Dongliang Zhao,Xiaoyan Wang,Yanchao Duan,Yaping Yan,Enqin Li,Kunhua Wu,Briauna Marie Inglis,Weizhi Ji,Ren-He Xu,Wei Si +13 more
TL;DR: The results demonstrate that human EMSC spheroids can prevent the osteoarthtitis progression and ameliorate osteOarthritis in the rhesus macaques as well as allogenic BMSCs, and this study shall help advance the clinical application of EMSCs.
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Noninvasive application of mesenchymal stem cell spheres derived from hESC accelerates wound healing in a CXCL12-CXCR4 axis-dependent manner.
Xiaoyan Wang,Bin Jiang,Huiyan Sun,Huiyan Sun,Dejin Zheng,Zhenwu Zhang,Li Yan,Enqin Li,Yaojiong Wu,Ren-He Xu +9 more
TL;DR: The topical application of EMSCSp as an unlimited, quality-assured, safe, and noninvasive therapy for wound healing and the CXCL12-CXCR4 axis as a key player in this treatment are suggested.
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