Li-Meng Yan
University of Hong Kong
5 Papers
4 Citations
Li-Meng Yan is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Vaccination & Influenza A virus. The author has an hindex of 3, co-authored 3 publications.
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Papers
Pathogenesis and transmission of SARS-CoV-2 virus in golden Syrian hamsters
Sin Fun Sia,Li-Meng Yan,Alex W.H. Chin,K. Fung,Leo L.M. Poon,John M. Nicholls,Malik Peiris,Hui-Ling Yen +7 more
- 01 Apr 2020
TL;DR: It is observed that the SARS-CoV-2 virus can be transmitted efficiently from the inoculated hamsters to co-housed naïve contact hamsters, and the results suggest that Sars-CoVs infection in golden Syrian hamsters resemble features found in human patients with mild infections.
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Combined use of live-attenuated and inactivated influenza vaccines to enhance heterosubtypic protection.
Li-Meng Yan,Olive T. W. Li,Chek M. Poh,Ranawaka A.P.M. Perera,Sophie A. Valkenburg,Malik Peiris,Leo L.M. Poon +6 more
TL;DR: A panel of sequential 4-dose immunization regimens tested the synergistic effect of combining different vaccine platforms to enhance heterosubtypic protection against influenza viruses and found the combined use of inactivated and live-attenuated vaccines could achieve the best heterological protection.
5
Peer Review
Unusual Features of the SARS-CoV-2 Genome Suggesting 1 Sophisticated Laboratory Modification as a Biological Robot 2 Rather than Natural Evolution and Delineation of Its Probable 3 Synthetic Route
Li-Meng Yan,Adrian David Cheok +1 more
TL;DR: In this article , the authors describe the genomic, structural, medical, and literature evidence that strongly contradicts the natural origin theory of SARS-CoV-2 and show that the evidence shows that SARSCoV2 should be a laboratory product created by using bat coronaviruses ZC45 and/or 19 ZXC21 as a template or backbone.
Pathogenesis and transmission of SARS-CoV-2 virus in golden Syrian hamsters
Sin Fun Sia,Li-Meng Yan,Alex W.H. Chin,Kevin Fung,Leo L.M. Poon,John M. Nicholls,Malik Peiris,Hui-Ling Yen +7 more
TL;DR: It is observed that the SARS-CoV-2 virus can be transmitted efficiently from the inoculated hamsters to co-housed naïve contact hamsters, and the results suggest that Sars-CoVs infection in golden Syrian hamsters resemble features found in human patients with mild infections.
The Hurdles From Bench to Bedside in the Realization and Implementation of a Universal Influenza Vaccine
Sophie A. Valkenburg,Nancy H. L. Leung,Maireid B. Bull,Li-Meng Yan,Athena P. Y. Li,Leo L.M. Poon,Benjamin J. Cowling +6 more
TL;DR: Improvements in vaccine design are needed to increase the strength, breadth, and duration of immunity against diverse strains that circulate during regular epidemics, occasional pandemics, and from animal reservoirs.