28 Papers
109 Citations
Li Lin is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Porphyromonas gingivalis & Chronic periodontitis. The author has an hindex of 10, co-authored 28 publications.
Chat about Author
Papers
Porphyromonas gingivalis survival skills: Immune evasion
Shaowen Zheng,Shiwen Yu,Xiaomiao Fan,Yonghuan Zhang,Yangyang Sun,Li Lin,Hongyan Wang,Yaping Pan,Chen Li +8 more
TL;DR: In this article, a review of studies devoted to understanding the strategies utilized by P. gingivalis to escape host immunity is presented, and methods for impairing immune evasion are also mentioned.
51
Porphyromonas gingivalis modulates Pseudomonas aeruginosa-induced apoptosis of respiratory epithelial cells through the STAT3 signaling pathway
Qian Li,Chunling Pan,Di Teng,Li Lin,Yurong Kou,Elaine M. Haase,Frank A. Scannapieco,Yaping Pan,Yaping Pan +8 more
TL;DR: Results suggest that regulation of P. aeruginosa-induced apoptosis by P. gingivalis contributes to the pathogenesis of respiratory disease and interference with this process may provide a potential therapeutic strategy for the treatment and prevention of respiratory Disease.
45
Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production
TL;DR: Nal-P-113 exhibited protective effects on Porphyromonas gingivalis-induced periodontitis in rats by limiting the amount of bacteria and modulating IL-1β and TNF-α production and might serve as a beneficial preventive or therapeutic approach forperiodontitis.
Porphorymonas gingivalis induces intracellular adhesion molecule‐1 expression in endothelial cells through the nuclear factor‐kappaB pathway, but not through the p38 MAPK pathway
TL;DR: The induction of ICAM-1 by infection of umbilical vein endothelial cells with P. gingivalis might be mediated through the NF-κB pathway, but not by the p38 MAPK pathway.
27
Sialidase Deficiency in Porphyromonas gingivalis Increases IL-12 Secretion in Stimulated Macrophages Through Regulation of CR3, IncRNA GAS5 and miR-21.
Xue Yang,Yaping Pan,Xiaoyu Xu,Tong Tong,Shiwen Yu,Yue Zhao,Li Lin,Jingbo Liu,Dongmei Zhang,Chen Li +9 more
TL;DR: The results indicate that inhibiting the activity of sialidase in P. gingivalis will cause rapid clearing by macrophages, which is more easily cleared by attenuating CR3 activation, reducing the inhibition of lncRNA GAS5, inducing less miR-21 and more IL-12 in macrophage.