Li-Jun Du
Tsinghua University
11 Papers
22 Citations
Li-Jun Du is an academic researcher from Tsinghua University. The author has contributed to research in topics: Berberine & Chemistry. The author has an hindex of 7, co-authored 11 publications. Previous affiliations of Li-Jun Du include Shandong University.
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Papers
Alkaloids from Portulaca oleracea L.
Lan Xiang,Dongming Xing,Dongming Xing,Wei Wang,Wei Wang,Rufeng Wang,Rufeng Wang,Yi Ding,Yi Ding,Li-Jun Du,Li-Jun Du +10 more
TL;DR: Five alkaloids (oleraceins A, B, C, D and E) were isolated from Portulaca oleracea L., and their structures determined by spectroscopic methods as 5-hydroxy-1-p-coumaric acyl-2,3-dihydro-1H-indole-2-carboxylic acid-6-O-beta-D-glucopyranoside, 5- hydroxy-1
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PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia-reperfusion.
Jun Hu,Yu-Shuang Chai,Yugang Wang,Michael M. Kheir,Michael M. Kheir,Huiying Li,Zhi-Yi Yuan,Hong-Jiao Wan,Dongming Xing,Fan Lei,Li-Jun Du +10 more
TL;DR: It is found that the anti-apoptotic effects of berberine against ischemia were indeed mediated by the increased phosphor-activation of Akt (higher p-Akt to total Akt), leading to the intensified phosphorylation of Bad and the decreased cleavage of the pro-APoptotic protease caspase-3.
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Inhibition of retinoblastoma mRNA degradation through poly (A) involved in the neuroprotective effect of berberine against cerebral ischemia
Yu-Shuang Chai,Zhi Yi Yuan,Fan Lei,Yu Gang Wang,Jun Hu,Feng Du,Xi Lu,Jing Fei Jiang,Dongming Xing,Li-Jun Du +9 more
TL;DR: The poly(A) tail of RB1 mRNA, as a newly identified target of berberine, could help people focus on the interaction between berberines and mRNA to further understand the biological activities and functions of berbertine.
Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling
Xin Pei Wang,Fan Lei,Feng Du,Yu-Shuang Chai,Jing Fei Jiang,Yu Gang Wang,Xuan Yu,Xiao Jin Yan,Dongming Xing,Li-Jun Du +9 more
TL;DR: A comprehensive mechanism by which berberine protects against gastrointestinal injuries from alcohol stress is reported, providing people with a novel application of BBR.
Investigation of quercetin stability in cell culture medium: Role in in vitro experiment
TL;DR: In this article, the authors investigated the stability of quercetin in Dulbecco's modified Eagle's medium (DMEM) and H2O at the cell culture pH range of 6 of 8 at continued time points, as well as 6 frequently used supplements in DMEM.
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