6 Papers
10 Citations
Li Jin is an academic researcher from Minzu University of China. The author has contributed to research in topics: Gene & Codon usage bias. The author has an hindex of 2, co-authored 5 publications.
Chat about Author
Papers
Peste Des Petits Ruminants Virus N Protein Is a Critical Proinflammation Factor That Promotes MyD88 and NLRP3 Complex Assembly
Lingxia Li,Wenping Yang,Xiaoxiao Ma,Jinyan Wu,Xiaodong Qin,Xiaoyan Cao,Jian Hua Zhou,Li Jin,Jijun He,Haixue Zheng,Xiangtao Liu,Dan Li,Youjun Shang +12 more
TL;DR: This study showed that PPRV induced the secretion of interleukin 1β (IL-1β) by activating the NF-κB signaling pathway and the NLRP3 inflammasome and demonstrated a new function of P PRV N protein as an important proinflammation factor and identify a novel underlying mechanism modulating inflammaome assembly and function induced by PPRv.
12
Antiviral responses of ATG13 to the infection of peste des petits ruminants virus through activation of interferon response.
Peng Ma,Lingxia Li,Li Jin,Derong Zhang,Xin Cao,Fucheng Guo,Yongqing Zhao,Jialing Bai,Zhongren Ma,Youjun Shang,Xiao-xia Ma +10 more
TL;DR: It is demonstrated that basal ATG 13 was involved in host antiviral activities against PPRV infection and the over-expression of ATG13 activated IFN production to inhibit PPRv replication in an unconventional fashion.
9
Significance and roles of synonymous codon usage in the evolutionary process of Proteus.
TL;DR: The results suggest that the mutation pressure caused by nucleotide composition constraint serves as a dominant evolutionary dynamic driving evolutionary trend of Proteus spp.
3
The nucleotide usages significantly impact synonymous codon usage in Mycoplasma hyorhinis.
Yaqin Wu,Li Jin,Yicong Li,Derong Zhang,Yongqing Zhao,Yuefeng Chu,Zhongren Ma,Xiao-xia Ma,Youjun Shang +8 more
TL;DR: In this article, five annotated genomes of Mycoplasma hyorhinis were analyzed for clarifying evolutionary dynamics driving the overall codon usage pattern, including nucleotide composition constraint derived from mutation pressure, translational selection involved in natural selection, and strand specific mutational bias represented by different nucleotide skew index.
Inhibiting pyrimidine biosynthesis impairs Peste des Petits Ruminants Virus replication through depletion of nucleoside pools and activation of cellular immunity
Li Jin,Yicong Li,Feiyang Pu,Huihui Wang,Derong Zhang,Jialin Bai,Youjun Shang,Zhongren Ma,Xiao-xia Ma +8 more
TL;DR: In this article, the authors demonstrate that brequinar and leflunomide (LFM) are two specific inhibitors of DHODH enzyme and 6-azauracil (6-AU) which is an ODase enzyme inhibitor robustly inhibit PPRV replication in HEK293T cell line as well as in peripheral blood mononuclear cells isolated from goat.