11 Papers
56 Citations
Li Fu is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Biology & Bacterial vaginosis. The author has an hindex of 6, co-authored 8 publications.
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Papers
Temporal Dynamics of the Human Vaginal Microbiota
Pawel Gajer,Rebecca M. Brotman,Guoyun Bai,Joyce M. Sakamoto,Ursel M. E. Schütte,Xue Zhong,Sara S. K. Koenig,Li Fu,Zhanshan Sam Ma,Xia Zhou,Zaid Abdo,Larry J. Forney,Jacques Ravel +12 more
TL;DR: The temporal dynamics of the composition of vaginal bacterial communities in 32 reproductive-age women over a 16-week period revealed the dynamics of five major classes of bacterial communities and showed that some communities change markedly over short time periods, whereas others are relatively stable.
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Ultrahigh-Throughput Multiplexing and Sequencing of >500-Base-Pair Amplicon Regions on the Illumina HiSeq 2500 Platform
Johanna B. Holm,Michael S. Humphrys,Courtney K. Robinson,Matthew L. Settles,Sandra Ott,Li Fu,Hongqiu Yang,Pawel Gajer,Xin He,Elias McComb,Patti E. Gravitt,Khalil G. Ghanem,Rebecca M. Brotman,Jacques Ravel +13 more
- 26 Feb 2019
TL;DR: Modifications to the Illumina HiSeq 2500 platform are described which produce greater multiplexing capabilities and 300-bp paired-end reads of higher quality than those produced by the current Illumina MiSeq platform.
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Insight into the ecology of vaginal bacteria through integrative analyses of metagenomic and metatranscriptomic data
M. France,Li Fu,Lindsay Rutt,Hongqiu Yang,Michael S. Humphrys,Shilpa Narina,Pawel Gajer,Bing Ma,Larry J. Forney,Jacques Ravel +9 more
TL;DR: In this article , the authors demonstrate that the abundance of a species is not always indicative of its transcriptional activity and that impending changes in community composition can be predicted from metatranscriptomic data.
Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota
Jacques Ravel,Pawel Gajer,Li Fu,Christine K. Mauck,Sara S. K. Koenig,Joyce M. Sakamoto,Alison A. Motsinger-Reif,Gustavo F. Doncel,Steven L. Zeichner,Steven L. Zeichner +9 more
TL;DR: The hypothesis that the microbicides negatively affect a critical line of defense against HIV, the vaginal microbiota, is tested, which suggests that molecular evaluation of microbicide effects on vaginal microbiota may be a critical endpoint that should be incorporated in early clinical assessment ofmicrobicide candidates.
Chlamydia caviae infection alters abundance but not composition of the guinea pig vaginal microbiota
Elizabeth Neuendorf,Pawel Gajer,Anne K. Bowlin,Patricia X. Marques,Bing Ma,Hongqiu Yang,Li Fu,Michael S. Humphrys,Larry J. Forney,Garry S. A. Myers,Patrik M. Bavoil,Roger G. Rank,Jacques Ravel +12 more
TL;DR: It is shown that the guinea pig and human vaginal microbiotas are of different bacterial composition and abundance, which compromise the validity of the Guinea pig-C.
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