Levi Arnold
University of Kansas
19 Papers
13 Citations
Levi Arnold is an academic researcher from University of Kansas. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Cancer. The author has an hindex of 5, co-authored 8 publications.
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Papers
Secretory autophagy in cancer-associated fibroblasts promotes head and neck cancer progression and offers a novel therapeutic target
Jacob New,Levi Arnold,Megha Ananth,Sameer Alvi,Mackenzie M. Thornton,Lauryn R. Werner,Ossama Tawfik,Hongying Dai,Yelizaveta Shnayder,Kiran Kakarala,Terance T. Tsue,Douglas A. Girod,Wen-Xing Ding,Shrikant Anant,Sufi M. Thomas +14 more
TL;DR: It is reported that autophagy is upregulated in HNSCC-associated CAFs, where it is responsible for key pathogenic contributions in this disease.
Cancer Stem Cell Metabolism and Potential Therapeutic Targets
TL;DR: Key factors that impact CSC metabolic phenotype including heterogeneity of CSCs across different histologic tumor types, tissue-specific variations, tumor microenvironment, and CSC niche are reviewed including targeting key players of glycolytic and mitochondrial pathways.
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Activated HGF-c-Met Axis in Head and Neck Cancer
TL;DR: The intertwining of c-Met signaling with other signaling pathways provides opportunities for more robust and specific therapies, leading to better clinical outcomes.
A Review of Promising Natural Chemopreventive Agents for Head and Neck Cancer.
TL;DR: 11 promising natural compounds in the chemopreventive efforts against head and neck squamous cell carcinoma are reviewed including vitamin A, curcumin, isothiocyanate, green tea, luteolin, resveratrol, genistein, lycopene, bitter melon, withaferin A, and guggulsterone.
Potent Antitumor Effects of a Combination of Three Nutraceutical Compounds.
Vikalp Vishwakarma,Jacob New,Dhruv Kumar,Dhruv Kumar,Vusala Snyder,Levi Arnold,Emily Nissen,Qingting Hu,Nikki Cheng,David Miller,Ahia Rael Thomas,Yelizaveta Shnayder,Kiran Kakarala,Terance T. Tsue,Douglas A. Girod,Sufi M. Thomas +15 more
TL;DR: Combining nutraceuticals is examined, establishing a combination therapy that is more potent than any singular component, and delineate the mechanism of action to demonstrate GZ17-6.02 as a highly effective plant extract combination and pave the way for future clinical application in HNSCC.