Leticia Nogueira
American Cancer Society
95 Papers
123 Citations
Leticia Nogueira is an academic researcher from American Cancer Society. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 18, co-authored 51 publications. Previous affiliations of Leticia Nogueira include Texas Department of State Health Services & National Institutes of Health.
Chat about Author
Papers
Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity
TL;DR: It is concluded that mTOR inhibition may be a pharmacologic strategy to mimic the anticancer effects of CR and break the obesity-breast cancer progression link.
Association of Aflatoxin With Gallbladder Cancer in Chile
Leticia Nogueira,Claudia Foerster,John D. Groopman,Patricia A. Egner,Jill Koshiol,Catterina Ferreccio +5 more
TL;DR: The association of aflatoxin with gallbladder cancer in humans has not been directly evaluated and exposure to aflat toxin is associated with bile duct epithelium proliferation in both animals and humans.
67
Differential Effects of Calorie Restriction and Exercise on the Adipose Transcriptome in Diet-Induced Obese Mice
Karrie E. Wheatley,Leticia Nogueira,Leticia Nogueira,Leticia Nogueira,Susan N. Perkins,Stephen D. Hursting,Stephen D. Hursting +6 more
TL;DR: Chromatin immunoprecipitation assays of the Glut4 promoter revealed that, relative to the DIO controls, CR significantly increased histone 4 acetylation, suggesting epigenetic regulation may underlie some of the differential effects of CR versus EX on the adipose transcriptome.
Dose‐dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin‐like growth factor‐1
Leticia Nogueira,Jackie A. Lavigne,Gadisetti V R Chandramouli,Huaitian Lui,J. Carl Barrett,Stephen D. Hursting +5 more
TL;DR: It is concluded that several genes and pathways, particularly those associated with macronutrient and steroid hormone metabolism, are associated with the anticancer effects of CR, and that reduced IGF‐1 levels can account, at least in part, for many of the effects ofCR on gene expression and mammary tumor burden.
56