Lesley Griffiths
University of Birmingham
52 Papers
815 Citations
Lesley Griffiths is an academic researcher from University of Birmingham. The author has contributed to research in topics: Escherichia coli & Excretion. The author has an hindex of 28, co-authored 52 publications. Previous affiliations of Lesley Griffiths include Nottingham Trent University.
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Papers
Metabolism of apigenin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro.
Lesley Griffiths,G. E. Smith +1 more
TL;DR: The rat intestinal microflora is capable of effecting degradation of flavonoid compounds to metabolites observed in the urine after oral administration of the specific flavonoids, and all compounds possessing free 5- and 7-hydroxyl groups in the A ring gave rise to ring-fission products, which included 4'-hydroxyphenylacyl derivatives.
237
Different physiological roles of two independent pathways for nitrite reduction to ammonia by enteric bacteria.
TL;DR: Data indicate that the Nir pathway provides a mechanism for detoxifying nitrite formed in the cytoplasm as a product of nitrate reduction, which provides a secondary source of energy during anaerobic growth and is consequently repressed by the NarL protein when the thermodynamically more favourable electron acceptor, nitrate, is available.
141
The roles of the polytopic membrane proteins NarK, NarU and NirC in Escherichia coli K‐12: two nitrate and three nitrite transporters
TL;DR: In contrast to NirC, which transports only nitrite, NarK and NarU provide alternative mechanisms for both nitrate and nitrite transport, however, NarU might selectively promote nitrite ex‐cretion, not nitrite uptake.
132
A reassessment of the range of c-type cytochromes synthesized by Escherichia coli K-12
Chantal Iobbi-Nivol,Helen Crooke,Lesley Griffiths,Jane I. Grove,Haitham Hussain,Janine Pommier,Vincent Méjean,J. A. Cole +7 more
TL;DR: Five different c-type cytochromes have been detected during anaerobic growth of various Escherichia coli strains in different media, but none of these cyto Chromes was detectable in aerobically-grown cultures.
96