Leroy Hood
Institute for Systems Biology
881 Papers
22.7K Citations
Leroy Hood is an academic researcher from Institute for Systems Biology. The author has contributed to research in topics: Gene & Biology. The author has an hindex of 158, co-authored 853 publications. Previous affiliations of Leroy Hood include Agency for Science, Technology and Research & Stowers Institute for Medical Research.
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Papers
Analysis of the Human Neurexin Genes: Alternative Splicing and the Generation of Protein Diversity
Lee Rowen,Janet M. Young,Brian Birditt,Amardeep Kaur,Anup Madan,Dana L. Philipps,Shizhen Qin,Patrick Minx,Richard K. Wilson,Leroy Hood,Brenton R. Graveley +10 more
TL;DR: The complete nucleotide sequence of all three human neurexin genes is determined and several conserved intronic sequence elements that may participate in the regulation of alternative splicing are identified.
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DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen
TL;DR: Gene transfer studies and comparison of the translated sequence with the partial amino acid sequence of the Ld transplantation antigen establish that gene 27.5 encodes an Ld polypeptide and suggests that the BALB/c mouse may contain a number of closely related L-like genes.
198
Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein
Bradford A. Jameson,Patricia E. Rao,Lilly I. Kong,Beatrice H. Hahn,George M. Shaw,Leroy Hood,Stephen B. H. Kent +6 more
TL;DR: It is proposed that a loop extending from residues 37 to 53 of the CD4 protein is a binding site for the AIDS virus.
197
Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.
Julian Schubert,Aleksandra Siekierska,Mélanie Langlois,Patrick May,Clément Huneau,Felicitas Becker,Hiltrud Muhle,Arvid Suls,Johannes R. Lemke,Carolien G.F. de Kovel,Holger Thiele,Kathryn Konrad,Amit Kawalia,Mohammad R. Toliat,Thomas Sander,Franz Rüschendorf,Almuth Caliebe,Inga Nagel,Bernard Kohl,Angela Kecskés,Maxime Jacmin,Katia Hardies,Sarah Weckhuysen,Erik Riesch,Thomas Dorn,Eva H. Brilstra,Stéphanie Baulac,Rikke S. Møller,Helle Hjalgrim,Bobby P. C. Koeleman,Karin Jurkat-Rott,Frank Lehman-Horn,Jared C. Roach,Gustavo Glusman,Leroy Hood,David J. Galas,Benoit Martin,Peter de Witte,Saskia Biskup,Peter De Jonghe,Ingo Helbig,Rudi Balling,Peter Nürnberg,Alexander D. Crawford,Camila V. Esguerra,Yvonne G. Weber,Holger Lerche +46 more
TL;DR: The results thus implicate STX1B and the presynaptic release machinery in fever-associated epilepsy syndromes.
196
Patent
A thermostable ligase mediated dna amplification system for the detection of genetic diseases
Francis Barany,John Zebala,Deborah A. Nickerson,Robert J. Kaiser,Leroy Hood +4 more
- 29 Apr 1991
TL;DR: In this article, the cloning of the gene of a thermophilic DNA ligase, from Thermus aquaticus strain HB8, was described, and the use of this ligase for the detection of specific sequences of nucleotides in a variety of nucleic acid samples.
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