Leonel E. Rojo
University of Santiago, Chile
46 Papers
224 Citations
Leonel E. Rojo is an academic researcher from University of Santiago, Chile. The author has contributed to research in topics: Medicine & Dementia. The author has an hindex of 19, co-authored 43 publications. Previous affiliations of Leonel E. Rojo include Arturo Prat University & University of Chile.
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Papers
Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease
Leonel E. Rojo,Leonel E. Rojo,Jorge Fernández,Andrea A. Maccioni,José M. Jiménez,Ricardo B. Maccioni +5 more
TL;DR: A solid set of discoveries has strengthened the idea that altered patterns in the glia-neuron interactions constitute early molecular events within the cascade of cellular signals that lead to neurodegeneration in AD.
363
The Role of Neuroimmunomodulation in Alzheimer's Disease
Ricardo B. Maccioni,Ricardo B. Maccioni,Leonel E. Rojo,Leonel E. Rojo,Leonel E. Rojo,Jorge Fernández,Rodrigo O. Kuljis +6 more
TL;DR: The damage signal hypothesis is proposed as a unifying scheme in that release of endogenous damage/alarm signals, in response to accumulated cell distress, is the earliest triggering event in AD, leading to activation of innate immunity and the inflammatory cascade.
270
Innovations in Health Value and Functional Food Development of Quinoa ( Chenopodium quinoa Willd.)
Brittany L. Graf,Patricio Rojas-Silva,Leonel E. Rojo,José Delatorre-Herrera,Manuel E. Baldeón,Ilya Raskin +5 more
TL;DR: Vast challenges and opportunities remain within the scientific, agricultural, and development sectors to optimize quinoa's role in the promotion of global human health and nutrition.
256
Insulin Resistance and Alzheimers Disease: Molecular Links & Clinical Implications
Karen F. Neumann,Leonel E. Rojo,Leonardo P Navarrete,Gonzalo A. Farías,Paula Reyes,Ricardo B. Maccioni +5 more
TL;DR: The potential molecular mechanisms that may explain the participation of these metabolic disorders in the pathogenesis of AD are discussed and the possible therapeutic targets in preventing the insulin-resistance disorders are analyzed.
251
In Vitro and in Vivo Anti-Diabetic Effects of Anthocyanins from Maqui Berry (Aristotelia chilensis).
Leonel E. Rojo,David M. Ribnicky,Sithes Logendra,Alexander Poulev,Patricio Rojas-Silva,Peter Kuhn,Ruth Dorn,Mary H. Grace,Mary Ann Lila,Ilya Raskin +9 more
TL;DR: It is observed that oral administration of ANC improved fasting blood glucose levels and glucose tolerance in hyperglycaemic obese C57BL/6J mice fed a high fat diet and D3S5G also increased glucose uptake in L6 myotubes and is at least partially responsible for ANC's anti-diabetic properties.
201