Leonardo M. Fabbri
University of Ferrara
579 Papers
7.1K Citations
Leonardo M. Fabbri is an academic researcher from University of Ferrara. The author has contributed to research in topics: COPD & Medicine. The author has an hindex of 109, co-authored 566 publications. Previous affiliations of Leonardo M. Fabbri include Imperial College London & University of California, San Francisco.
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Papers
Peripheral eosinophil count as a biomarker for the management of COPD: not there yet
TL;DR: These drugs are effective agents for the prevention of COPD exacerbations and improvement of lung function and have various effects on health status, but they are associated with adverse events, the most concerning being pneumonia (ICS) and diarrhoea (roflumilast).
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Eosinophil cationic protein (ECP), histamine and tryptase in peripheral blood before and during inhalation challenge with toluene diisocyanate (TDI) in sensitized subjects
Cristina E. Mapp,Mario Plebani,Diego Faggian,Piero Maestrelli,Marina Saetta,P. G. Calcagni,Franco Borghesan,Leonardo M. Fabbri +7 more
TL;DR: The results suggest that eosinophils arc ‘activated’ in subjects who develop a late asthmatic reaction after exposure to TDI and that the measurement of ECP levels in peripheral blood may be a useful marker to monitor airway inflammation.
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Fatal asthma attack during an inhalation challenge with ultrasonically nebulized distilled water.
Marina Saetta,Antonino Di Stefano,Graziella Turato,Raffaele De Caro,Daniele Bordignon,Stephen T. Holgate,Leonardo M. Fabbri +6 more
TL;DR: This work has shown that protein measurement with the folin phenol reagent reduces the chances of tarantula-induced papular dermatitis in animals and also helps clarify the mechanism behind the injury in humans.
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Oxygen radical scavengers inhibit clastogenic activity induced by sonication of human serum.
Silvano Pinamonti,Milvia Chicca,Mariavittoria Muzzoli,Alberto Papi,Leonardo M. Fabbri,Adalberto Ciaccia +5 more
TL;DR: The results suggest that the clastogenic activity generated by sonication of human serum is mediated by oxygen radicals.
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Bronchopulmonary inflammation and airway smooth muscle hyperresponsiveness induced by nitrogen dioxide in guinea pigs.
Alberto Papi,Silvia Amadesi,Pasquale Chitano,Piera Boschetto,Adalberto Ciaccia,Pierangelo Geppetti,Leonardo M. Fabbri,Cristina E. Mapp +7 more
TL;DR: It is shown that in vivo exposure to high concentrations of NO2 induces major inflammatory responses in guinea pig airways that mimic acute bronchitis induced by exposure to irritant gases in man.
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