Leonardo Guizzetti
University of Western Ontario
58 Papers
36 Citations
Leonardo Guizzetti is an academic researcher from University of Western Ontario. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 34 publications.
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Papers
Efficacy of Medical Therapies for Fistulizing Crohn's Disease: Systematic Review and Meta-analysis.
Matthew Lee,Matthew Lee,Claire E Parker,Sarah R. Taylor,Leonardo Guizzetti,Brian G. Feagan,Alan J Lobo,Vipul Jairath,Vipul Jairath +8 more
TL;DR: TNF antagonists were found to be effective for induction and maintenance of perianal fistula response and remission and low‐quality evidence for the efficacy of vedolizumab and immunosuppressives was found.
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An International Consensus to Standardize Integration of Histopathology in Ulcerative Colitis Clinical Trials
Christopher Ma,Rocio Sedano,Ahmed Almradi,Niels Vande Casteele,Claire E Parker,Leonardo Guizzetti,David F. Schaeffer,Robert H. Riddell,Reetesh K. Pai,Robert Battat,Bruce E. Sands,Christophe Rosty,Marla Dubinsky,Florian Rieder,Noam Harpaz,Maria T. Abreu,Robert V Bryant,Gregory Y. Lauwers,Richard Kirsch,Mark A. Valasek,Eileen Crowley,William J. Sandborn,Brian G. Feagan,Rish K. Pai,Vipul Jairath +24 more
TL;DR: In this paper, an international, interdisciplinary expert panel of 19 gastroenterologists and gastrointestinal pathologists was assembled to provide guidance on standardizing biopsy collection protocols, identifying optimal evaluative indices, and defining thresholds for histologic response and remission after treatment.
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Development of Clinical Prediction Models for Surgery and Complications in Crohn's Disease.
Leonardo Guizzetti,Guangyong Zou,Reena Khanna,Parambir S. Dulai,William J. Sandborn,William J. Sandborn,Vipul Jairath,Brian G. Feagan +7 more
TL;DR: Separate risk prediction models for Crohn's disease-related surgery and complications were developed using clinical trial data involving community gastroenterology practices and could be used to guide Crohn’s disease management.
CORE-IBD: A Multidisciplinary International Consensus Initiative to Develop a Core Outcome Set for Randomized Controlled Trials in Inflammatory Bowel Disease.
Christopher Ma,Jurij Hanžel,Remo Panaccione,William J. Sandborn,Geert R. D'Haens,Vineet Ahuja,Raja Atreya,Charles N. Bernstein,Peter Bossuyt,Brian Bressler,Robert V Bryant,Benjamin L Cohen,Jean-Frederic Colombel,Silvio Danese,Axel Dignass,Marla Dubinsky,Phillip Fleshner,Richard B. Gearry,Stephen B. Hanauer,Ailsa Hart,Paulo Gustavo Kotze,Torsten Kucharzik,Peter L. Lakatos,Rupert W. Leong,Fernando Magro,Julián Panés,Laurent Peyrin-Biroulet,Zhihua Ran,Miguel Regueiro,Siddharth Singh,Antonino Spinelli,A. Hillary Steinhart,Simon Travis,C. Janneke van der Woude,Bruce R. Yacyshyn,Takayuki Yamamoto,Matthieu Allez,Willem A. Bemelman,Amy L. Lightner,Edouard Louis,David T. Rubin,Ellen Scherl,Corey A. Siegel,Mark S. Silverberg,Severine Vermeire,Claire E Parker,S. Mcfarlane,Leonardo Guizzetti,Michelle I. Smith,Niels Vande Casteele,Brian G. Feagan,Vipul Jairath +51 more
TL;DR: This multidisciplinary collaboration involving patients and clinical experts has produced the first COS that can be applied to RCTs of Crohn's disease and UC.
Assessing National Trends and Disparities in Ambulatory, Emergency Department, and Inpatient Visits for Inflammatory Bowel Disease in the United States (2005–2016)
Christopher Ma,Matthew K. Smith,Leonardo Guizzetti,Remo Panaccione,Gilaad G. Kaplan,Kerri L. Novak,Cathy Lu,Reena Khanna,Brian G. Feagan,Siddharth Singh,Vipul Jairath,Ashwin N. Ananthakrishnan +11 more
TL;DR: It is found that although IBD-related ambulatory visits stabilized-to-decreased from 2005 through 2016, rates of ED use and admission to the hospital have continued to increase with changes in patient demographics, over time and among care settings.
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