Leon Edwards
Liverpool Hospital
15 Papers
12 Citations
Leon Edwards is an academic researcher from Liverpool Hospital. The author has contributed to research in topics: Medicine & Stroke (engine). The author has an hindex of 2, co-authored 10 publications. Previous affiliations of Leon Edwards include University of New South Wales & Royal Prince Alfred Hospital.
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Papers
Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial
Peter Mitchell,Bernard Yan,Leonid Churilov,Richard Dowling,Steven Bush,Andrew Bivard,Xiao Huo,Guoqing Wang,Shiyong Zhang,Mai Duy Ton,Dennis Cordato,Timothy Kleinig,Henry Hin Kui Ma,Ronil V. Chandra,Helen Brown,Bruce C.V. Campbell,Andrew Cheung,Brendan Steinfort,Rebecca Scroop,Kendal Redmond,F. Miteff,Yang Liu,Dang Phuc Duc,Henry E. Rice,Mark W Parsons,Teddy Y. Wu,Huy Thang Nguyen,Geoffrey A. Donnan,Zhongrong Miao,Stephen M. Davis,Patricia Desmond,Nawaf Yassi,Henry Zhao,Cameron Williams,Fana Alemseged,Felix C Ng,Vignan Yogendrakumar,Peter L. Bailey,L. de Villiers,Thanh G. Phan,Tharani Thirugnanachandran,Winston Chong,Hamed Asadi,Lee-Anne Slater,Nathan W Manning,Jason Wenderoth,Alan McDougall,Cecilia Cappelen-Smith,Justin T. Whitley,Leon Edwards,Carlos Garcia-Esperon,Neil J. Spratt,E. Pepper,Christopher R Levi,Kenneth Faulder,Timothy Harrington,Martin Krause,Michael J. Waters,J. Fink,Gaoting Ma,Xiangpeng Shen,Xiang-jun Song,Yong-jian Gao,Nam Guangxian,Zaiyu Guo,Heliang Zhang,Hongxing Han,Hao Wang,Geng Liao,Zhenyu Zhang,Chaomao Li,Zhihua Yang,Chuwei Cai,Chuming Huang,Yifan Hong +74 more
TL;DR: The clinical outcomes of patients with stroke with large vessel occlusion treated with direct endovascular thrombectomy within 4·5 h would be non-inferior compared with the outcomes of those treated with standard bridging therapy, as well as the intention-to-treat population, were hypothesized.
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Impact of interhospital transfer on patients undergoing endovascular thrombectomy for acute ischaemic stroke in an Australian setting.
Leon Edwards,Christopher Blair,Dennis Cordato,Alan McDougall,Nathan W Manning,Andrew Cheung,Jason Wenderoth,Cecilia Cappelen-Smith +7 more
- 05 Apr 2020
TL;DR: Interhospital transfer is associated with longer stroke onset to treatment, worse 90-day functional outcome and higher mortality compared with patients presenting directly to the CSC, an analysis of a prospective database of consecutive patients undergoing EVT for LVO.
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Comparison of functional outcomes after endovascular thrombectomy in patients with and without atrial fibrillation
James Fu,Cecilia Cappelen-Smith,Leon Edwards,Andrew Cheung,Nathan W Manning,Jason Wenderoth,Mark W Parsons,Dennis Cordato +7 more
- 23 Jun 2021
TL;DR: Patients with atrial fibrillation showed improved 90-day functional outcome, with similar mortality and sICH, after EVT, and Therapeutic anticoagulation did not adversely influence EVT outcomes.
Optimal CT perfusion thresholds for core and penumbra in acute posterior circulation infarction
Leon Edwards,Cecilia Cappelen-Smith,Dennis Cordato,Andrew Bivard,Leonid Churilov,Longting Lin,Chushuang Chen,Carlos Garcia-Esperon,Kenneth Butcher,Timothy Kleinig,Phillip M. Choi,Xin Cheng,Qiang Dong,Richard I. Aviv,Mark W Parsons +14 more
TL;DR: In this paper , the optimal thresholds for defining core and penumbra in POCI were defined based on the area under the curve (AOC) of the voxel-based analysis.
Intravenous Thrombolysis Is Associated with Less Disabling Stroke and Lower Mortality in Multiple-Pass Endovascular Thrombectomy.
Christopher Blair,Christopher Blair,Leon Edwards,Leon Edwards,Cecilia Cappelen-Smith,Cecilia Cappelen-Smith,Dennis Cordato,Dennis Cordato,Andrew Cheung,Andrew Cheung,Jason Wenderoth,Alex McQuinn,Alex McQuinn,Nathan W Manning +13 more
TL;DR: In this article, the benefit of bridging intravenous thrombolysis (IVT) in acute ischaemic stroke patients eligible for endovascular thrombectomy (EVT) is examined.
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