Lene Helleskov Madsen
University of Copenhagen
6 Papers
20 Citations
Lene Helleskov Madsen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Troponin I & Troponin. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Lene Helleskov Madsen include University of Oslo.
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Papers
Incremental value of a combination of cardiac troponin T, N-terminal pro-brain natriuretic peptide and C-reactive protein for prediction of mortality in end-stage renal disease.
Jonas Hallén,Lene Helleskov Madsen,Søren Ladefoged,Morten W. Fagerland,Victor L. Serebruany,Stefan Agewall,Stefan Agewall,Dan Atar,Dan Atar +8 more
TL;DR: The results suggest that cTnT and CRP can be used in combination for risk stratification in patients with ESRD and highlight the additive effect they confer in this regard.
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Comparison of four different cardiac troponin assays in patients with end-stage renal disease on chronic haemodialysis.
TL;DR: The prognostic value of cTNT appears superior to cTnI, which amplifies the prognostic significance of this cardiovascular marker in patients with ESRD, which diverging results in previous studies are most likely based on substantial differences in the analytical performance of the assays.
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•Journal Article
Molekylære forandringer af troponin I og T påvist i serum hos patienter med akut myokardieinfarkt
TL;DR: This pilot study defines, for the first time, what forms of cTnI and cTtnT appear in the bloodstream of AMI patients, and it clarifies the lack of standardization between different cTNI diagnostic assays.
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Echocardiographic indices of left ventricular diastolic dysfunction in 647 individuals with preserved left ventricular systolic function.
TL;DR: It is necessary to select patients suitable for vaginal or laparoscopic mesh placement for diastolic dysfunction based on prior history and once they provide informed consent for surgery.
Time Course of Degradation of Cardiac Troponin I in Patients With Acute ST-Elevation Myocardial Infarction The ASSENT-2 Troponin Substudy
Lene Helleskov Madsen,Lene Helleskov Madsen,Geir Christensen,Terje Lund,Victor L. Serebruany,Christopher B. Granger,Ingvild B Hoen,Zanina Grieg,John H. Alexander,Allan S. Jaffe,Jennifer E. Van Eyk,Dan Atar +11 more
TL;DR: Intact cTnI and a single degradation product were detectable on immunoblot as early as 90 minutes after onset of symptoms with further degradation after 165 minutes, defining for the first time the initial time course of cardiac troponin I degradation in STEMI.