Lena Wester
Lund University
8 Papers
81 Citations
Lena Wester is an academic researcher from Lund University. The author has contributed to research in topics: Arthritis & Recombinant DNA. The author has an hindex of 7, co-authored 8 publications. Previous affiliations of Lena Wester include University of Rostock.
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Papers
Arthritis induced in rats with non-immunogenic adjuvants as models for rheumatoid arthritis
Rikard Holmdahl,Johnny C. Lorentzen,Johnny C. Lorentzen,Shemin Lu,Peter Olofsson,Lena Wester,Jens Holmberg,Ulf Pettersson +7 more
TL;DR: In this article, the authors proposed a disease-oriented genetic approach to unravel the mechanisms behind adjuvant-induced rheumatoid arthritis in rats, and found several loci that control onset of arthritis, severity and chronicity of the disease.
Receptor for alpha1-microglobulin on T lymphocytes: inhibition of antigen-induced interleukin-2 production.
TL;DR: The results suggest that α1m binds to a specific receptor on T cells and that the binding leads to inhibition of antigen‐stimulated IL‐2 production by T‐helper cells.
52
Physicochemical and biochemical characterization of human alpha 1-microglobulin expressed in baculovirus-infected insect cells
TL;DR: It can be concluded that bikunin is not necessary for an adequate translation, folding, and secretion of alpha 1-microglobulin, and it may prove to be useful in structural and functional studies of the protein.
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Chronicity of pristane-induced arthritis in rats is controlled by genes on chromosome 14
TL;DR: It is concluded that the active relapsing chronic arthritis is under a unique genetic control that is different from the control of acute arthritis and postulate that the liver plays an important role in this regulation.
25
Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats
Lena Wester,Dirk Koczan,Jens Holmberg,Peter Olofsson,Hans-Jürgen Thiesen,Rikard Holmdahl,Saleh M. Ibrahim +6 more
TL;DR: Animal models are well suited for reproducible microarray analysis of candidate genes for arthritis, and all genes have functions that are potentially important for arthritis and nine of the genes are located within genomic regions previously associated with autoimmune disease.