Lekhika Pathak
Indian Institute of Technology Guwahati
20 Papers
2 Citations
Lekhika Pathak is an academic researcher from Indian Institute of Technology Guwahati. The author has contributed to research in topics: Stem cell & Biology. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Lekhika Pathak include Indian Institutes of Technology.
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Papers
Coronavirus Activates an Altruistic Stem Cell-Mediated Defense Mechanism that Reactivates Dormant Tuberculosis: Implications in Coronavirus Disease 2019 Pandemic.
Lekhika Pathak,Sukanya Gayan,Bidisha Pal,Joyeeta Talukdar,Seema Bhuyan,Sorra Sandhya,Herman Yeger,Debabrat Baishya,Bikul Das +8 more
TL;DR: In this article, a mesenchymal stem cell (MSC)-based altruistic defense against a mouse model of coronavirus, murine hepatitis virus-1 (MHV-1) infection of lung.
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The emerging role of oral microbiota in oral cancer initiation, progression and stemness
TL;DR: The role of oral microbiota has been explored with a special focus on how oral microbiota induces OSCC initiation and stemness by modulating the oral mucosal stem cell and CSC niche defense.
20
Initiation of Post-Primary Tuberculosis of the Lungs: Exploring the Secret Role of Bone Marrow Derived Stem Cells.
TL;DR: In this paper, the role of bone marrow (BM) stem cell niche in Mtb dormancy and reactivation was explored, which may underlie the mechanisms of PPTBL development.
Corona virus activates a stem cell mediated defense mechanism that accelerates activation of dormant tuberculosis: implications for the COVID-19 pandemic
Lekhika Pathak,Sukanya Gayan,Bidisha Pal,Bidisha Pal,Joyeeta Talukdar,Seema Bhuyan,Sorra Sandhya,Herman Yeger,Debabrat Baishya,Debabrat Baishya,Bikul Das,Bikul Das +11 more
TL;DR: The data suggest that MSCs exert an innate defense against MHV-1 by activating the ASC defense mechanism, which might be exploited by dormant Mtb to undergo reactivation, which may provide a novel anti-viral defense mechanism against novel corona virus SARS-Cov2.
Coronavirus activates a stem cell-mediated defense mechanism that reactivates dormant tuberculosis: implications in COVID-19 pandemic
Lekhika Pathak,Sukanya Gayan,Bidisha Pal,Bidisha Pal,Joyeeta Talukdar,Seema Bhuyan,Sorra Sandhya,Herman Yeger,Debabrat Baishya,Debabrat Baishya,Bikul Das,Bikul Das +11 more
TL;DR: In this article, a mouse model of mesenchymal stem cells (MSC) mediated Mycobacterium tuberculosis (Mtb) dormancy was used to develop a vaccine against COVID-19.
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