Leif Busk
National Food Administration
26 Papers
239 Citations
Leif Busk is an academic researcher from National Food Administration. The author has contributed to research in topics: Vitamin & Ames test. The author has an hindex of 13, co-authored 26 publications.
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Papers
Risk assessment of substances that are both genotoxic and carcinogenic: Report of an International Conference organized by EFSA and WHO with support of ILSI Europe
Susan Barlow,Andrew G. Renwick,Juliane Kleiner,James W. Bridges,Leif Busk,E. Dybing,Lutz Edler,Gerhard Eisenbrand,Johanna Fink-Gremmels,A. Knaap,Rob Kroes,Djien Liem,D.J.G. Müller,S. Page,V. Rolland,Josef Rudolf Schlatter,Angelika Tritscher,W. Tueting,G. Würtzen +18 more
TL;DR: The margin of exposure (MOE) was the preferred approach because it is based on the available animal dose-response data, without extrapolation, and on human exposures, and there was consensus that it is difficult to interpret it in terms of health risk.
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Dietary exposure assessments for children in Europe (the EXPOCHI project): rationale, methods and design
Inge Huybrechts,Isabelle Sioen,Polly Boon,Jiri Ruprich,Lionel Lafay,Aida Turrini,Pilar Amiano,T. Hirvonen,Melissa De Neve,Davide Arcella,Joanna Moschandreas,Anna Westerlund,Lourdes Ribas-Barba,Annett Hilbig,Stalo Papoutsou,Tue Christensen,Maciej Oltarzewski,Suvi M. Virtanen,Irena Rehurkova,Mikel Azpiri,Stefania Sette,Mathilde Kersting,Alicja Walkiewicz,Luis Serra-Majem,Luis Serra-Majem,Jean-Luc Volatier,Ellen Trolle,Michael Tornaritis,Leif Busk,Anthony Kafatos,Stefan Fabiansson,Stefaan De Henauw,Jacob D. van Klaveren +32 more
TL;DR: The EXPOCHI project includes a pan-European long-term exposure assessment of lead, chromium, selenium and food colours among children living in 13 different EU countries, and the different study methods and designs used to collect the data in the different countries necessitate an in-depth description of these different methods and a discussion about the resulting limitations.
Evaluation of the DNA damaging effect of the heat-induced food toxicant 5-hydroxymethylfurfural (HMF) in various cell lines with different activities of sulfotransferases.
TL;DR: HMF is shown to be a DNA damaging agent in vitro independent of the activity of SULT1A1 in the cells, which usually was associated with a concomitant decrease in cell viability.
108
The SAFE FOODS framework for improved risk analysis of foods
Ariane König,Harry A. Kuiper,Hans J.P. Marvin,Polly Boon,Leif Busk,F. Cnudde,S.F. Cope,Howard V. Davies,Marion Dreyer,Lynn J. Frewer,Matthias Kaiser,Gijs Kleter,Ib Knudsen,G Pascal,Aldo Prandini,Ortwin Renn,M. R. Smith,Bruce Traill,H. van der Voet,H.C.M. van Trijp,Ellen Vos,M.T.A. Wentholt +21 more
TL;DR: In this article, three main changes to current risk analysis processes are proposed to improve their transparency, openness, and accountability, including the addition of a formal framing stage to allow interested parties, experts and officials to work together as needed to gain an initial shared understanding of the issue, the objectives of regulatory action, and alternative risk management measures.
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Genotoxic activity of 1,3-butadiene and nitrogen dioxide and their photochemical reaction products in Drosophila and in the mouse bone marrow micronucleus assay.
TL;DR: The genotoxic activity of a photochemical reaction mixture of 1,3-butadiene and nitrogen dioxide was investigated in vivo in the mouse bone marrow micronucleus assay and the somatic mutation and recombination test in Drosophila (the wing spot test).
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