6 Papers
111 Citations
Lei Wang is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Syk & Tumor suppressor gene. The author has an hindex of 4, co-authored 4 publications.
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Papers
Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1).
Yong Pan,Lei Wang,Jia Le Dai +2 more
TL;DR: The putative NHERF1 tumour suppressor activity has not been functionally verified as discussed by the authors, but it is known that loss of heterozygosity (LOH) occurs in more than 50% of breast cancer cells.
Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression.
TL;DR: It is shown that the full-length form of Syk acts as a transcription repressor in the cell nucleus and interacts with transcription factor Sp1 at the Sp1 DNA-binding site in the F RA1 promoter to repress Sp1-activated FRA1 transcription.
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PET/MR Imaging of a Lung Metastasis Model of Clear Cell Renal Cell Carcinoma with (2S,4R)-4-[18F]Fluoroglutamine
Alyssa C. Pollard,Vincenzo Paolillo,Bhasker Radaram,S. Qureshy,Li Li,Tapati Maity,Lei Wang,Md. Nasir Uddin,Christopher G. Wood,Jose A. Karam,Mark Pagel,David Piwnica-Worms,Steven W. Millward,Natalie Wall Fowlkes,William Norton,Brian J. Engel,Federica Pisaneschi,N. Zacharias +17 more
TL;DR: In this paper , the authors used (2S,4R)-4]-18Ffluoroglutamine ([18F]FGln) to interrogate altered glutamine metabolism in ccRCC lesions in the lung.
Expression characteristic, immune signature, and prognosis value of EFNA family identified by multi-omics integrative analysis in pan-cancer
TL;DR: In this article , a comprehensive landscape of EphrinA (EFNA) was created using various statistical data extracted from 33 cancers, and the clinical features and diagnostic prognostic value of EFNAs were investigated.
3
NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer.
TL;DR: Results indicated NHERF to be a candidate tumor suppressor gene in human breast carcinoma that may be interconnected to the SYK and MERLIN suppressors.