8 Papers
1 Citations
Lei Li is an academic researcher from East China Normal University. The author has contributed to research in topics: Cycloaddition & Carbon–carbon bond. The author has an hindex of 5, co-authored 8 publications.
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Papers
Lewis Acid-catalyzed [3 + 2]Cyclo-addition of Alkynes with N-Tosyl-aziridines via Carbon–Carbon Bond Cleavage: Synthesis of Highly Substituted 3-Pyrrolines
TL;DR: A novel, efficient, and highly regioselective Lewis acid-catalyzed [3 + 2] cycloaddition of alkynes with azomethine ylides, which are easily obtained from N-tosylaziridines via C-C bond heterolysis at room temperature was developed.
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Lewis acid-catalyzed formal [3+2] cycloadditions of N-tosyl aziridines with electron-rich alkenes via selective carbon-carbon bond cleavage.
TL;DR: A novel, mild, robust catalyst Y(OTf)(3) for C-C bond heterolysis of N-tosyl aziridines was developed and the resulting metallo-azomethine ylides may readily undergo [3+2] dipolar cycloaddition with an electron-rich olefin via a stepwise reaction pathway with high regio- and diastereoselectivity leading to substituted pyrrolidines.
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Direct Aza-Darzens Aziridination of N-Tosylimines with 2-Bromomalonates for the Synthesis of Highly Functionalized Donor-Acceptor Aziridines
TL;DR: In this paper, an approach to highly functionalized donor-acceptor aziridines by the azirideination of N-tosylimines and 2-bromomalonates in the presence of sodium hydride under mild conditions has been developed.
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Nickel(II)-Catalyzed Diastereoselective [3 + 2] Cycloaddition of N-Tosyl-aziridines and Aldehydes via Selective Carbon—Carbon Bond Cleavage.
TL;DR: In this article, an efficient and mild Ni(ClO4)2-catalyzed cycloaddition of N-tosylaziridines and aldehydes via C-C bond cleavage was developed.
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Direct Aza-Darzens Aziridination of N-Tosylimines with 2-Bromomalonates for the Synthesis of Highly Functionalized Donor—Acceptor Aziridines.
TL;DR: The wide substrate scope, excellent yield, simple operating and purification procedures are advantages of the described method.