Lee N. Graham
Leeds General Infirmary
21 Papers
79 Citations
Lee N. Graham is an academic researcher from Leeds General Infirmary. The author has contributed to research in topics: Catheter ablation & Medicine. The author has an hindex of 11, co-authored 21 publications. Previous affiliations of Lee N. Graham include University of Leeds & Leeds Teaching Hospitals NHS Trust.
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Papers
Relationship between central sympathetic activity and stages of human hypertension
TL;DR: Central sympathetic activity was greatest in BHT, early stage, and complicated EHT, and as such is likely to play an integral role in the development of hypertension and its complications.
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Sympathetic neural mechanisms in white-coat hypertension.
TL;DR: It was shown, in the clinical setting, that central sympathetic hyperactivity exists in white-coat hypertension, albeit to a lesser degree than EHT, suggesting that WHT may not be entirely benign and that the observed sympatheticHyperactivity may be responsible for development of target organ damage in this group of patients.
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Gender differences in sympathetic neural activation following uncomplicated acute myocardial infarction.
TL;DR: Following uncomplicated AMI, women developed a relatively greater magnitude of sympathetic activation lasting until its resolution at 9 months, consistent with reports of their worse prognosis observed during this time period, with important potential clinical implications.
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Left atrial voltage, circulating biomarkers of fibrosis, and atrial fibrillation ablation. A prospective cohort study.
Gordon A. Begg,Gordon A. Begg,Rashed Karim,Tobias Oesterlein,Lee N. Graham,Andrew J. Hogarth,Stephen P. Page,Chris Pepper,Kawal Rhode,Gregory Y.H. Lip,Gregory Y.H. Lip,Arun V. Holden,Sven Plein,Muzahir H. Tayebjee +13 more
TL;DR: Four circulating biomarkers of fibrosis, and of low left atrial voltage, to predict recurrence of atrial fibrillation after catheter ablation were tested, irrespective of the rhythm during mapping.
Relationship of neurovascular compression to central sympathetic discharge and essential hypertension.
Paul A. Smith,James F.M Meaney,Lee N. Graham,John B. Stoker,Alan F. Mackintosh,David A.S.G. Mary,Stephen G. Ball +6 more
TL;DR: Investigating the relationship between neurovascular compression of the rostral ventrolateral medulla (RVLM) and the magnitude of central sympathetic hyperactivity in normal subjects and in patients with untreated and uncomplicated essential hypertension found increased sympathetic activity was strongly predictive of NVC.
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