Anti-inflammatory activity of the extracts of ginseng berry (GBE) was investigated through the evaluation of its inhibitory effect on the production of inflammatory meditator, nitric oxide(NO), tumor necrocis factor-alpha (TNF-α), interleukin-6 (IL-6) in LPS-induced RAW264.7 macrophage cells. GBE was fractionated using n-hexane, chloroform, ethy- lacetate, buthanol and H2O, sequentially. RAW264.7 cells were induced 100 ng/㎖ of lipopolysaccharide (LPS) and treated with 0, 1.6, 8, 40 and 200 ㎍/㎖ of GBE fractions. LPS-induced NO production on all of GBE fractions was inhibited with increasing added concentration of GBE fractions. Chloroform fraction of GBE was the most effective in inhibiting LPS- induced TNF-α production. Hexane, chloroform and H2O fractions of GBE exhibit strong inhibition LPS-induced IL-6 pro- duction. Especially, H2O fractions of GBE was the most effective in inhibiting LPD-induced IL-6 production without signifi- cant cytotoxicity in RAW264.7 cells, and reduced the activation of mitogen-activated protein kinases (MAPK) and IkB phosphorylation. These results indicate that H2O fractions of GBE exhibits strong anti-inflammatory effects by inhibition of NF-kB by inhibition of p-38 on MAPK and IkB phosphorylation.

Anti-inflammatory Activity of Solvent Fractions from Ginseng Berry Extract in LPS-Induced RAW264.7 Cells

Disclosed are feed for improving immunity prepared by blending natural substances to strengthen immunity of puppies and sick dogs vulnerable to diseases by the invasion of an external pathogen due to weak immunity; and a method for preparing the same. According to the present invention, the feed for improving an immunity function is prepared by mixing rice flour, powdered skim milk, hydrolysis poultry powder, Echinacea (extract), propolis (liquid), yeast beta gluten (powder), fermented red ginseng (powder), and shiitake mushroom (extract) at a predetermined ratio. A method for preparing feed to improve an immunity function comprises a preparing step, a blending step, an extruding and forming step, a drying step, a crushing and screening step, and a packing step.

Feed for improving immunity and manufacturing method for the feed

The present invention relates to a novel strain of Saccharomyces cerevisiae HJ-014 (KACC93219P) with ginsenoside bioconversion ability, and to a manufacturing method of a fermented red ginseng extract using the same. β-glucosidase producing yeast is isolated from Korean traditional rice wine, especially Makgeolli, and is identified. The novel yeast strain can effectively produce a compound K from a crude ethanol extract of ginseng. A manufacturing method of a fermented red ginseng extract comprises steps of inoculating a red ginseng extract with a strain of Saccharomyces cerevisiae HJ-014 (KACC93219P), and cultivating the strain.

Strain having ginsenoside bioconversion activity and manufacturing method of fermented red ginseng extract using the same

The present invention relates to composition for enhancing immunity, comprising ginsenoside F1 as an active ingredient. Specifically, the composition according to the present invention promotes degranulation activity and cell-killing activity of natural killer cells, and increases expressions of cell-killing factors, thereby being effectively used as an immune enhancer.

Composition for enhancing immunity including ginsenoside f1 as an active ingredient

The present invention relates to a pharmaceutical composition, a functional health food, and a feed composition for preventing, ameliorating, or treating non-alcoholic liver disease or insulin resistance, containing ginsenoside F2. According to the present invention, the pharmaceutical composition containing ginsenoside F2 suppresses production and accumulation of fat in liver and increases insulin sensitivity. In addition, the pharmaceutical composition also suppresses expression of inflammatory cytokines in Kupffer cells such as TNF-, IL-1, and IL-6, and also suppresses expression of endocannabinoid synthase, thereby effectively preventing or treating non-alcoholic liver disease or insulin resistance.

A composition comprising ginsenoside f2 for preventing or treating non-alcoholic liver disease

PURPOSE: A fermentation method is provided to have maximum effect of ginseng and red ginseng through fermentation and excellent strain screening on fermentation of ginseng or red ginseng. CONSTITUTION: A ginseng or red ginseng extract is manufactured. After filtering the ginseng or red ginseng extract, the extraction is sterilized at 80-90 degree Celsius for 25-45 minutes. After sterilized ginseng or red ginseng extract is cooled, 3-5% (v/v) ferment strain is added to ferment at 25-30 degree Celsius for 3-7 days. After filtering the ferment extract, the extractionis concentrated at 45 degree Celsius water phase by using a rotary vacuum evaporator. The condensed product is stored at a deep freezer for 10-15 hours and freeze dried from a freeze dryer. The condensed product has 38-52% of solid content. [Reference numerals] (AA) Prepare ginseng or red ginseng; (S10) Manufacture a ginseng or red ginseng extract; (S20) Filter and sterilize; (S30) Inoculate ferment strain and ferment; (S40) Filter and concentrate; (S50) Freeze-dry

Method for fermenting the ginseng or red ginseng and the fermented ginseng or red ginseng made thereby

The present invention relates to fermented-ginseng containing increased ginsenoside Rd using pectinase and a preparation method of fermented-red ginseng. The preparation method according to the present invention can economically change the structure of a small amount of ginsenoside Rd contained in ginseng or red ginseng. The present invention allows preparation of fermented-ginseng or fermented-red ginseng which has ginsenoside Rd which has no cytotoxicity, is easily absorbed into the body, and has functional activities. [Reference numerals] (AA) Red ginseng extract (12 Brix);(BB) Add coenzyme (10%, w/w) at 50 and cultivate for three days;(CC) Sterilize at 95 for ten minutes;(DD) Cool down;(EE) Inoculate L.Plantarum;(FF) Cultivate at 37 for two days;(GG) Sterilize at 95 for ten minutes;(HH) Concentrate at 60 with reduced pressure;(II) Rd-improved fermented red ginseng

Preparation for fermented-red gingseng or fermented-gingseng containing increased ginsenoside rd using pectinase

The present invention relates to a feed additive composition for pet showing immunity improvement effects and anti-obesity effects by comprising crude saponin of ginseng leaves as an active ingredient The feed additive composition of the present invention is prepared by the steps of: adding 70% ethanol into dried ginseng leaves and extracting the same for 6 to 8 hours at 45 to 90°C; filtering, decompressing, and concentrating the extract and preparing an ethanol extract; adding n-hexane into the ethanol extract, extracting the same, and removing fat-soluble components; adding water and water saturated n-BuOH into the extract in which the fat-soluble components are removed, and dividing the same; and collecting the divided n-BuOH layer, and decompressing and concentrating the same

Feed additives for pet animal containing ginseng leaves

The present invention relates to an external use composition for promoting hair growth or inhibiting hair loss which includes ginsenoside F2 derived from fermented red ginseng as an active ingredient. The composition according to the present invention has enhanced stability and no side effects on skin and excellent effects of hair loss inhibition and hair growth by the fact that ginsenoside F2 helps follicular cell activation, thereby promoting hair growth and delaying hair loss.

A composition comprising ginsenoside f2 for promoting hair growth or inhibiting hair loss

The present invention relates to a production method of a ginseng berry extract which concentrates ginsenoside Re which is a main component of ginseng berries without applying heat to the ginseng berries, and is capable of producing powder from the ginseng berry extract to economically and easily obtain the ginseng berry extract with the reinforced ginsenoside Re from the ginseng berries.

Preparation for the extract of ginseng berry containing increased ginsenoside re

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Lee Kun Hee

Author Tools

Chat about Author