Le Bu
Tongji University
54 Papers
93 Citations
Le Bu is an academic researcher from Tongji University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 29 publications. Previous affiliations of Le Bu include Second Military Medical University.
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Papers
Melatonin improves non-alcoholic fatty liver disease via MAPK-JNK/P38 signaling in high-fat-diet-induced obese mice.
TL;DR: It is concluded that melatonin could improve NAFLD by decreasing body weight and reduce inflammation in HFD induced obese mice by modulating the MAPK-JNK/P38 signaling pathway.
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Eosinophils Reduce Chronic Inflammation in Adipose Tissue by Secreting Th2 Cytokines and Promoting M2 Macrophages Polarization
TL;DR: The role of eosinophils in regulating metabolic homeostasis and obesity is focused on.
The Associations of Serum Uric Acid with Obesity-Related Acanthosis nigricans and Related Metabolic Indices.
Cuiling Zhu,Ran Cui,Mingming Gao,Sharvan Rampersad,Hui You,Chunjun Sheng,Peng Yang,Hui Sheng,Xiaoyun Cheng,Le Bu,Shen Qu +10 more
TL;DR: Serum UA levels were positively associated with multiple metabolic abnormalities including obesity, hypertension, hyperglycemia, hyperlipidemia, and AN and may be an important risk factor in the development of AN.
Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse
TL;DR: The work showed that the course of β-cell dedifferentiation can intervene by long-term control of calorie intake, and key β- cell-specific TFs and functional factors play important roles in maintainingβ-cell differentiation.
J-shaped association between fasting blood glucose levels and COVID-19 severity in patients without diabetes.
Bing Zhu,Shengwei Jin,Lianpeng Wu,Chenchan Hu,Zhen Wang,Le Bu,Hang Sun,Xingchun Wang,Shen Qu,Dong Chen +9 more
TL;DR: Evidence of J-shaped associations between FBG and risk of severe and critical condition in non-diabetes patients with COVID-19 is provided, with nadir at 4.74-5.78 mmol/L.
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