LC Goldstein
3 Papers
5 Citations
LC Goldstein is an academic researcher. The author has contributed to research in topics: Oncotype DX & Surgical oncology. The author has an hindex of 1, co-authored 2 publications.
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Papers
Population-based study of hormone receptor status comparing Oncotype DX with standard immunohistochemistry.
Frederick L. Baehner,Tara Maddala,C Alexander,AM Gown,LC Goldstein,Ninah S. Achacoso,S Shak,Charles P. Quesenberry,Laurel A. Habel +8 more
TL;DR: Data accumulated over the past decade have provided evidence that breast cancer surveillance can be improved with the addition of breast MRI, that prophylactic oophorectomy substantially reduces the risk of ovarian cancer and, when performed before menopause, can reduce therisk of breast cancer as well, and that proPHylactic mastectomy reduces the Risk of Breast cancer by more than 90%.
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A quantitative universal NGS-based circulating tumor DNA assay for hepatoblastoma
Smadar Kahana-Edwin,James Torpy,Lucy E. Cain,Alan Mullins,G McCowage,Sarah E. Woodfield,Swetha Vasudevan,D. Shea,André E. Minoche,S. Kummerfeld,LC Goldstein,Jonathan Karpelowsky +11 more
TL;DR: Approximate quantitation of various variants including single base substitutions and deletions down to 0.3% variant allele frequency is demonstrated to allow biopsy-free tumor genotyping and sensitive ct DNA quantitation, providing promising evidence for the utility of quantitative ctDNA detection in hepatoblastoma.
HER2 assessment using fluorescence in situ hybridization compared with Oncotype DX and association with risk of breast cancer death
Frederick L. Baehner,Ninah S. Achacoso,Tara Maddala,C Alexander,S Shak,Charles P. Quesenberry,LC Goldstein,AM Gown,Laurel A. Habel +8 more
TL;DR: Data accumulated over the past decade have provided evidence that breast cancer surveillance can be improved with the addition of breast MRI, that prophylactic oophorectomy substantially reduces the risk of ovarian cancer and, when performed before menopause, can reduce therisk of breast cancer as well, and that proPHylactic mastectomy reduces the Risk of Breast cancer by more than 90%.