Laurence Legros
French Institute of Health and Medical Research
207 Papers
1K Citations
Laurence Legros is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Imatinib mesylate & Medicine. The author has an hindex of 38, co-authored 186 publications. Previous affiliations of Laurence Legros include Centre national de la recherche scientifique & University of Nice Sophia Antipolis.
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Papers
Long-Term Follow-up of Ongoing Patients in 2 Studies of Omacetaxine Mepesuccinate for Chronic Myeloid Leukemia.
Hagop M. Kantarjian,Jeffrey H. Lipton,Michele Baccarani,Franck E. Nicolini,Meir Wetzler,Luke P. Akard,Laurence Legros,Krzysztof Warzocha,Adam R. Craig,Jorge E. Cortes +9 more
TL;DR: This ad hoc analysis presents the efficacy and safety results of patients in the phase 2 studies of chronic myeloid leukemia who remained on omacetaxine as of March 31, 2012 and pooled from patients with CML chronic phase (CML-CP) and CML accelerated phase ( CML-AP).
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A phase II study of the efficacy and safety of an intensified schedule of azacytidine in intermediate-2 and high-risk patients with myelodysplastic syndromes: a study by the Groupe Francophone des Myelodysplasies (GFM)
Lionel Ades,Agnès Guerci-Bresler,Pascale Cony-Makhoul,Laurence Legros,Marie Sebert,Thorsten Braun,Jacques Delaunay,Kristell Desseaux,Sylvie Chevret,Pierre Fenaux +9 more
TL;DR: Although Azacytidine improves survival over conventional treatments in higher-risk myelodysplastic syndromes (MDS), the marrow response rate remains low [complete remission (CR) + partial remission (PR) rate of].
Clinical Added Value of SARS-CoV-2 Antigen Detection in Blood Samples
Saoussen Oueslati,Melek Manai Manai Bouokazi,Ikrame Ramdhani,Lélia Escaut,Tài Pham,Souad Ouzani,Nadia Anguel,Sophie Bulifon,Christelle Vauloup-Fellous,Audrey Coilly,Laurence Legros,Magali Guichardon,Nicolas Fortineau,Laurent Dortet,Anne-Marie Roque-Afonso,Thierry Naas +15 more
TL;DR: Sensitive immunoassays designed for SARS-CoV-2 Antigen (Ag)-detection in nasopharyngeal (NP) and serum samples are suitable COVID-19-laboratory diagnostic tests, particularly when blood samples are available, thus reducing the requirement for NP sampling, and subsequent PCR analysis.
Pegylated Interferon Alpha-2a Therapy for Patients with High Risk Essential Thrombocytemia: a Retrospective Analysis on 59 Patients.On Behalf of the French Intergroup of Myeloproliferative Disorders (FIM)
Lydia Roy,Jean Christophe Ianotto,Joelle Guilhot,Emmanuel Raffoux,Emmanuel Gyan,Benoit de Renzis,Laurence Legros,Jean-François Viallard,Françoise Boyer,Cony Makhoul,Franck E. Nicolini,Jean Gunecht,Stéphane Giraudier +12 more
TL;DR: A retrospective analysis of cases of high risk ET having being or currently treated with IFN-α and reported by centres of the French Intergroup of myeloproliferative disorders (FIM) found the superior toxicity profile is generally associated with a rapid hematologic response.
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