Laura Tribouillard
Laval University
6 Papers
Laura Tribouillard is an academic researcher from Laval University. The author has contributed to research in topics: mTORC1 & GTPase. The author has an hindex of 2, co-authored 3 publications.
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Papers
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
Hijai R. Shin,Y. Rose Citron,Lei Wang,Laura Tribouillard,Claire Goul,Robin Stipp,Yusuke Sugasawa,Aakriti Jain,Nolwenn Samson,Chun-Yan Lim,Oliver B. Davis,David Castaneda-Carpio,Ming-Yi Qian,Daniel K. Nomura,Rushika M. Perera,Eun Young Park,Douglas F. Covey,Mathieu Laplante,Alex S. Evers,Roberto Zoncu +19 more
TL;DR: This work has identified LYCHOS, a multidomain transmembrane protein that enables cholesterol-dependent activation of the master growth regulator, the protein kinase mechanistic Target of Rapamycin Complex 1 (mTORC1).
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Control of adipogenic commitment by a stat3-vstm2a axis
Manal Al Dow,Maruhen Amir Datsch Silveira,Audrée Poliquin,Laura Tribouillard,Eric Fournier,Eva Trébaol,Blandine Secco,Romain Villot,Félix Tremblay,Steve Bilodeau,Mathieu Laplante +10 more
TL;DR: It is reported that Vstm2a expression is positively regulated by PI3K/mTOR and cAMP-dependent signaling pathways and repressed by the MAPK pathway and the glucocorticoid receptor.
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
Celia de la Calle Arregui,Ana Belén Plata-Gómez,Nerea Deleyto-Seldas,Fernando García,Ana Ortega-Molina,Julio Abril-Garrido,Elena Rodríguez,Ivan Nemazanyy,Laura Tribouillard,Alba de Martino,Eduardo Caleiras,Ramón Campos-Olivas,Francisca Mulero,Mathieu Laplante,Javier Munoz,Mario Pende,Guadalupe Sabio,David M. Sabatini,Alejo Efeyan +18 more
TL;DR: In this paper, the authors showed that constitutive nutrient signaling to mTORC1 by means of genetic activation of RagA (expression of GTP-locked RagA, or "RagAGTP") in mice resulted in a fatal energetic crisis at birth.
Generation and characterization of a Cre-inducible ZNF768 overexpression mouse model
Audrey Poirier,Laura Tribouillard,Manal Kordahi,Yves Gélinas,Joanny Roy,Marie-Josée Beaulieu,Michèle Orain,Marie-Renée Blanchet,Philippe Joubert,Mathieu Laplante +9 more