Laura Sormani
French Institute of Health and Medical Research
11 Papers
14 Citations
Laura Sormani is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Vitiligo & T cell. The author has an hindex of 5, co-authored 8 publications. Previous affiliations of Laura Sormani include University of Queensland.
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Papers
Melanocytes Sense Blue Light and Regulate Pigmentation through Opsin-3.
Claire Regazzetti,Laura Sormani,Delphine Debayle,Françoise Bernerd,Meri K. Tulic,Gian Marco De Donatis,B. Chignon-Sicard,Stéphane Rocchi,Thierry Passeron +8 more
TL;DR: Evidence is provided showing that OPN3 is the key sensor in melanocytes responsible for hyperpigmentation induced by the shorter wavelengths of visible light, and the multimeric tyrosinase/tyrosinases-related protein complex induced after its activation appears as new potential targets for regulating melanogenesis.
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Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo
Meri K. Tulic,Elisa Cavazza,Yann Cheli,Arnaud Jacquel,Carmelo Luci,Nathalie Cardot-Leccia,Hanene Hadhiri-Bzioueche,Patricia Abbe,Maeva Gesson,Laura Sormani,Claire Regazzetti,Guillaume E. Beranger,Cedric Lereverend,Caroline Pons,Abdallah Khemis,Robert Ballotti,Corine Bertolotto,Stéphane Rocchi,Thierry Passeron +18 more
TL;DR: NK and ILC1 cells are increased in vitiligo patients, and induce melanocyte apoptosis via CXCR3B, which in turn leads to increased priming of T cell responses in cell culture.
Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors.
Jilai Zhao,Jatin Patel,Jatin Patel,Simranpreet Kaur,Seen Ling Sim,Ho Yi Wong,Cassandra Styke,Isabella Hogan,Sam L. Kahler,Hamish Hamilton,Racheal Wadlow,James Dight,Ghazaleh Hashemi,Laura Sormani,Edwige Roy,Mervin C. Yoder,Mathias Francois,Kiarash Khosrotehrani +17 more
TL;DR: In this article, the authors show that conditional knock-out of Sox9 from the vasculature (Sox9fl/fl/Cdh5-CreER RosaYFP) depletes EVP while enhancing Rbpj expression and canonical Notch signalling.
Differential expression of CXCL9, CXCL10, and IFN-γ in vitiligo and alopecia areata patients.
TL;DR: C-X-C motif chemokine receptor 3 (CXCR3) and its ligand 9, CXCL9, CxCL10 and CXCl11, are linked to the Th1 pattern and have been suggested as one of the most relevant Chemokine axes that promote T cell migration in different autoimmune and inflammatory processes.
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