Laura A. Banaszynski
University of Texas Southwestern Medical Center
47 Papers
282 Citations
Laura A. Banaszynski is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Chromatin & Biology. The author has an hindex of 20, co-authored 37 publications. Previous affiliations of Laura A. Banaszynski include Stanford University & Rockefeller University.
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Papers
HP1γ self-assembles and cooperates with KAP1 in repression of long noncoding RNA AI662270 in ESCs.
Nitika Gaurav,Weihua Qin,Karthik Selvam,Z. Zhou,Jiuyang Liu,Yanshuang Yin,Rohit K. Singh,Ryan O’Hara,Zohreh Tavaf,Hidetoshi Kono,Geeta J. Narlikar,Laura A. Banaszynski,Heinrich Leonhardt,Tatiana G. Kutateladze +13 more
The length of G1 phase is an essential determinant of H3K27me3 landscape across diverse cell types.
Abby Trouth,Kamesh Ravichandran,Philip R. Gafken,Sara Martire,Gabriel E Boyle,Giovana M. B. Veronezi,Van La,Stephanie J Namciu,Laura A. Banaszynski,Jay F. Sarthy,Srinivas Ramachandran +10 more
A Directed Approach for Engineering Conditional Protein Stability Using Biologically Silent Small Molecules
Lystranne A. Maynard-Smith,Ling chun Chen,Laura A. Banaszynski,A. G.Lisa Ooi,Thomas J. Wandless +4 more
TL;DR: This study used FKBP12 as a model system and found that in vitro thermodynamic stability correlates weakly with intracellular degradation rates of the mutants and that the ability of a given mutation to destabilize the protein is context-dependent.
Chemical control of protein stability and function in living mice
Laura A. Banaszynski,Mark A. Sellmyer,Christopher H. Contag,Thomas J. Wandless,Steve H. Thorne,Steve H. Thorne +5 more
TL;DR: regulation of secreted proteins and their biological activity with conditional secretion of an immunomodulatory cytokine, resulting in tumor burden reduction in mouse models and suggests uses for enhancing the specificity and efficacy of targeted gene-based therapies.
A transcriptional biosensor reveals mechanisms of α-ketoglutarate signaling to chromatin
Alex C. Sternisha,Haocheng Li,Jeffrey I. Traylor,Lei Guo,Ji Hyung Jun,Xin Zhao,Kumar Gajendra,Ouyang Qing,Michael Schmidt,Morgan Fleishman,Milan R. Savani,Yi Xiao,Joyce H. Lee,Lauren G Zacharias,Thomas P Mathews,Ruth Gordillo,Lin Xu,John G. Doench,Vidyasagar Koduri,Kalil G. Abdullah,Laura A. Banaszynski,Michalis Agathocleous,Ralph J. DeBerardinis,Eric M. Morrow,Samuel K. McBrayer +24 more