Larry Moran
University of Geneva
5 Papers
322 Citations
Larry Moran is an academic researcher from University of Geneva. The author has contributed to research in topics: Heat shock protein & Gene. The author has an hindex of 5, co-authored 5 publications.
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Papers
The Effect of Heat Shock on Gene Expression in Drosophila melanogaster
TL;DR: This chapter elaborates the effect of heat shock on gene expression in drosophila melanogaster by identifying the de novo synthesized poly(A) + RNA found in these polyribosomes sediments as two main component which includes a major fraction of 20 S RNA predominant in the large poly ribosomes, and a minor 12 S fraction found mostly in small polyribsomes.
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Two hybrid plasmids with D. melanogaster DNA sequences complementary to mRNA coding for the major heat shock protein
Paul Schedl,Spyridon Artavanis-Tsakonas,Ruth Steward,Walter J. Gehring,Marc Edouard Mirault,Michel Goldschmidt-Clermont,Larry Moran,Alfred Tissières +7 more
TL;DR: Two cloned segments of Drosophila melanogaster DNA containing "heat shock" gene sequences hybridize in situ to the heat-induced puff sites located at 87A and 87C of the salivary gland polytene chromosomes.
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Physical map of two D. melanogaster DNA segments containing sequences coding for the 70,000 dalton heat shock protein.
Larry Moran,Marc-Edouard Mirault,Alfred Tissières,John T. Lis,Paul Schedl,Spyros Artavanis-Tsakonas,Walter J. Gehring +6 more
TL;DR: The results show that the two cloned Dm DNA segments derive from nonoverlapping regions of the Dm genome; that they contain homologous regions present once in 56H8 and twice in 132E3; and that each homologueous region is composed of three distinct contiguous sequence elements, x, y and z, which together define a 3 kb common unit.
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Genes for the 70,000 dalton heat shock protein in two cloned D. melanogaster DNA segments.
TL;DR: It is reported here that the sequences complementary to the 70,000 dalton protein mRNA appear to be confined to a major portion of the largest element of the common unit and that the other sequence elements are located at the 5' end of the gene.
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Heat Shock of Drosophila melanogaster Induces the Synthesis of New Messenger RNAs and Proteins
TL;DR: The heat shock proteins, labelled in vivo with [35S]methionine, were separated by sodium dodecylsulphate-polyacrylamide gel electrophoresis and fingerprinted after tryptic digestion to characterize eight distinct heat shock polypeptides.