Lara Leoni
University of Chicago
25 Papers
90 Citations
Lara Leoni is an academic researcher from University of Chicago. The author has contributed to research in topics: Nanoporous & Islet. The author has an hindex of 14, co-authored 22 publications. Previous affiliations of Lara Leoni include University of Illinois at Urbana–Champaign & University of Illinois at Chicago.
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Papers
Influence of engineered titania nanotubular surfaces on bone cells.
TL;DR: In vivo biocompatibility results suggest that nanotubular titania does not cause chronic inflammation or fibrosis, and the fabrication routes of titania nano-architectures are flexible and cost-effective, enabling realization of desired platform topologies on existing non-planar orthopedic implants.
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Nanoporous anti-fouling silicon membranes for biosensor applications.
TL;DR: Results indicate that micromachined silicon membranes can be fabricated with uniform pore sizes capable of the simultaneous exclusion of albumin and diffusion of glucose, and point to the potential of using such membranes for implantable biosensor applications.
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Biocompatibility of nanoporous alumina membranes for immunoisolation
Kristen E La Flamme,Ketul C. Popat,Lara Leoni,Erica Markiewicz,Thomas J. La Tempa,Brian B. Roman,Craig A. Grimes,Tejal A. Desai,Tejal A. Desai +8 more
TL;DR: In vivo work has demonstrated that implantation of these capsules into the peritoneal cavity of rats induces a transient inflammatory response, and that PEG is useful in minimizing the host response to the material.
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Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma
Shih-Hsun Cheng,Dou Yu,Hsiu-Ming Tsai,Ramin A. Morshed,Deepak Kanojia,Leu Wei Lo,Lara Leoni,Yureve Govind,Lingjiao Zhang,Karen S. Aboody,Maciej S. Lesniak,Chin-Tu Chen,Irina V. Balyasnikova +12 more
TL;DR: A novel strategy for mesoporous silica nanoparticle (MSN)–facilitated NSC tracking in the brain via SPECT and it is discovered that decayed 111In-MSN complexes exhibit strong fluorescent profiles in preloaded NSCs, allowing for ex vivo validation of the in vivo data.
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Nanoporous Platforms for Cellular Sensing and Delivery
TL;DR: The creation of monodisperse nanoporous, biocompatible, silicon membranes as a platform for the delivery of cells using silicon based substrates with cells of interest in terms of viability, proliferation, and functionality is described.
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