Lang Chen
Central South University
9 Papers
Lang Chen is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Lang Chen include Houston Methodist Hospital.
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Papers
Microbiota regulate innate immune signaling and protective immunity against cancer
Changsheng Xing,Mingjun Wang,Adebusola A. Ajibade,Peng Tan,Chuntang Fu,Lang Chen,Motao Zhu,Motao Zhu,Zhao Zhe Hao,Junjun Chu,Junjun Chu,Xiao Yu,Bingnan Yin,Bingnan Yin,Jiahui Zhu,Wan Jou Shen,Tianhao Duan,Tianhao Duan,Helen Yicheng Wang,Rongfu Wang +19 more
TL;DR: This article found that loss of the innate and adaptive immune signaling molecule, TAK1, in myeloid cells (Tak1ΔM/ ΔM) yields complete resistance to chemical-induced colitis and colorectal cancer through microbiome alterations that drive protective immunity.
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The Risk of Rheumatoid Arthritis among Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
Yi Chen,Lang Chen,Changsheng Xing,Guangtong Deng,Furong Zeng,Tingting Xie,Lei Gu,Hui Xiang Yang +7 more
TL;DR: Patients with IBD have a greater risk of developing RA and rheumatologists should be consulted when patients with I BD present with undifferentiated joint complaints, however, more prospective cohort studies are needed to validate these results.
BECN2 (beclin 2) Negatively Regulates Inflammasome Sensors Through ATG9A-Dependent but ATG16L1- and LC3-Independent Non-Canonical Autophagy.
Guangtong Deng,Guangtong Deng,Chaoran Li,Chaoran Li,Lang Chen,Lang Chen,Changsheng Xing,Changsheng Xing,Chuntang Fu,Chuntang Fu,Chen Qian,Chen Qian,Xin Liu,Xin Liu,Helen Yicheng Wang,Helen Yicheng Wang,Motao Zhu,Motao Zhu,Rongfu Wang +18 more
TL;DR: In this article, the authors showed that loss of BECN2 enhanced the activities of NLRP3, AIM2, NLRP1, and NLRC4 inflammasomes upon ligand stimulations.
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EZH2: An Accomplice of Gastric Cancer
WuHan Yu,Ning Liu,Xiaowen Song,Lang Chen,Man Cai Wang,Guohui Xiao,Tengfei Li,Zheyuan Wang,Youcheng Zhang +8 more
TL;DR: The role of EZH2 in the progression of gastric cancer is discussed in this article , where the authors provide a detailed description of the mechanism and progress in the development of inhibitors.
Clinicopathological and prognostic significance of nestin expression in patients with breast cancer: a systematic review and meta-analysis
Xinyi Zhang,Xinyi Zhang,Changsheng Xing,Wenting Guan,Wenting Guan,Lang Chen,Lang Chen,Kai Guo,Anze Yu,Anze Yu,Kai Xie,Kai Xie,Kai Xie +12 more
TL;DR: Nestin is a promising therapeutic target for malignant breast cancer, especially for TNBC and basal-like phenotype, and an independent prognostic factor for worse BCSS and OS of breast cancer patients.