Lan Yang
Chinese Academy of Sciences
4 Papers
Lan Yang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Autoantibody. The author has an hindex of 1, co-authored 2 publications.
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Papers
MGMT autoantibodies as a potential prediction of recurrence and treatment response biomarker for glioma patients.
Haibin Wu,Zhitong Deng,Hao Wang,Xuetao Li,Ting Sun,Zhennan Tao,Lin Yao,Yanping Jin,Wang Xiaoying,Lan Yang,Hongwei Ma,Yulun Huang,Youxin Zhou,Ziwei Du +13 more
TL;DR: The objective of this study is to investigate the clinical utility of serum O‐6‐methylguanine‐DNA methyltransferase (MGMT) autoantibodies as novel biomarkers for prediction of recurrence and treatment response for glioma through MGMT peptides microarray.
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Previously unrecognized non-reproducible antibody-antigen interactions and their implications for diagnosis of viral infections including COVID-19
Jiaojiao Pan,Jiaojiao Pan,Lan Yang,Yi Deng,Yi Deng,Baoqing Sun,Li Zhang,Wenya Wu,Wenya Wu,Jingzhi Li,Cheng Hu,Cheng Hu,Li Yiting,Wenwen Xu,Jiao Yang,Sun Yiyue,Sun Yiyue,Hao Fei,Qinghong Xue,Youxin Zhou,Hui Wang,Peiyan Zheng,Hao Chen,Feng Cai Zhu,Daxin Peng,Jun Han,Jiwan Qiu,Hongwei Ma +27 more
TL;DR: In this article, the authors showed that non-specific interactions (NSI) comprise a substantial proportion of non-reproducible antibody-based results and developed a powerful explanatory model that is [mAb]-dependent, regardless of specificity, which ultimately shows that both NSI and NRI are not predictable yet certain-to-happen.
Utilizing Protein–Peptide Hybrid Microarray for Time-Resolved Diagnosis and Prognosis of COVID-19
Peiyan Zheng,Baolin Liao,Jiao Yang,Huei-Ling Cheng,Zhangkai J Cheng,Huimin Huang,Wenting Luo,Yiyue Sun,Qiang Zhu,Yi Deng,Lan Yang,Yuxi Zhou,Wenya Wu,Shanhui Wu,Weiping Cai,Yeping Li,Xiaoneng Mo,Xinghua Tan,Linghua Li,Hongwei Ma,Baoqing Sun +20 more
TL;DR: PPM technology has the potential to be a powerful tool for tracking the dynamic changes of antibodies in the serum of COVID-19 patients and for improving the diagnosis and prognosis of the disease.
Removing Negative Impacts from Inevitable Nonreproducible and Nonspecific Antibody-Probe Interactions in Viral Serology.
Wenwen Xu,Hao Chen,Yiting Li,Huei-Ling Cheng,Peiyan Zheng,Jingzhi Li,Lan Yang,Shiping He,Dongli Ma,Q. Zhu,Dayong Gu,Jun Han,Baoqing Sun,Hongwei Ma +13 more
TL;DR: In this paper , the authors developed a new serological platform that integrates recent understanding about antibody specificity, i.e., antibody (Ab) specificity, and demonstrated that the response rate (RR) from a large-sized serum pool (∼100) is not affected by NRIs or by nonspecific Ab-probe interactions (NSIs).