Lan Chen
Chinese Academy of Sciences
5 Papers
42 Citations
Lan Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 3, co-authored 4 publications.
Chat about Author
Papers
Identifying Hfq-binding small RNA targets in Escherichia coli.
Yong Zhang,Shiwei Sun,Tao Wu,Jie Wang,Changning Liu,Lan Chen,Xiaopeng Zhu,Yi Zhao,Zhihua Zhang,Baochen Shi,Hongchao Lu,Runsheng Chen +11 more
TL;DR: The Hfq-binding small RNAs have recently drawn much attention as regulators of translation in Escherichia coli and a new alignment algorithm was used to identify the targets in genome scale and gain further insight into the complexity of translational regulation induced by HfqsRNAs.
25
Dynamic changes in subgraph preference profiles of crucial transcription factors.
Zhihua Zhang,Changning Liu,Geir Skogerbø,Xiaopeng Zhu,Hongchao Lu,Lan Chen,Baochen Shi,Yong Zhang,Jie Wang,Tao Wu,Runsheng Chen +10 more
TL;DR: Normalized abundances of basic regulatory patterns of individual THubs in the yeast Saccharomyces cerevisiae transcriptional regulation network under five different cellular states and environmental conditions suggest switching of regulatory pattern preferences suggests that a change in conditions does not only elicit achange in response by the regulatory network, but also in the mechanisms by which the response is mediated.
Assessing TF regulatory relationships of divergently transcribed genes.
TL;DR: It is found that most of the previously characterized regulatory associations reported in the literature fell into the HC group rather than the LC group, and genomic distance analysis showed that TF binding sites tend to be located in relative proximity to the gene that is most likely to be regulated by this TF.
2
NPInter: the noncoding RNAs and protein related biomacromolecules interaction database
Tao Wu,Jie Wang,Changning Liu,Yong Zhang,Baochen Shi,Xiaopeng Zhu,Zhihua Zhang,Geir Skogerbø,Lan Chen,Hongchao Lu,Yi Zhao,Runsheng Chen +11 more
TL;DR: The NPInter will be useful for understanding ncRNA function, as it adds a very important functional element, ncRNAs, to the biomolecule interaction network and sets up a bridge between the coding and the noncoding kingdoms.