L. Verhoeff
4 Papers
L. Verhoeff is an academic researcher. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 1, co-authored 3 publications.
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Papers
Longitudinal Serum Protein Analysis of Women with a High Risk of Developing Breast Cancer Reveals Large Interpatient Versus Small Intrapatient Variations: First Results from the TESTBREAST Study
Sophie C. Hagenaars,Lennard J. M. Dekker,B. Ravesteijn,Ronald L.P. van Vlierberghe,Fred P.H.T.M. Romijn,L. Verhoeff,Arjen J Witkamp,K. E. Schenk,Kristien Keymeulen,Marian B. E. Menke-Pluijmers,A.E. Dassen,Birgitta Kortmann,Jakob de Vries,Emiel J. Th. Rutgers,Yuri E. M. van der Burgt,Elma Meershoek-Klein Kranenbarg,Christa M. Cobbaert,Theo M. Luider,Wilma E. Mesker,Rob A. E. M. Tollenaar +19 more
TL;DR: Strong clustering patterns within longitudinal intrapatient samples have demonstrated the importance of identifying small changes in protein levels for individuals over time, underlines the significance of longitudinal serum measurements, that patients can serve as their own controls, and the relevance of the current study set-up for early detection.
Identifying a protein panel for early cancer detection for women at high risk for breast cancer; first results from the multicenter TESTBREAST study
Sophie C. Hagenaars,B. Ravesteijn,Lennard J. M. Dekker,L. Verhoeff,Jan J.J. Aalberts,Elma Meershoek-Klein Kranenbarg,Jakob de Vries,Arjen J Witkamp,K. E. Schenk,Kristien Keymeulen,Marian B. E. Menke-Pluijmers,A.E. Dassen,Birgitta Kortmann,Emiel J. Th. Rutgers,Christa M. Cobbaert,Theo M. Luider,Wilma E. Mesker,Rob A. E. M. Tollenaar +17 more
TL;DR: In this paper , a panel of blood-based protein biomarkers that enables early detection of breast cancer for high-risk women using liquid biopsies was identified. But the timing of screening is still an issue, amongst others due to the occurrence of interval cancers and because imaging is not possible during pregnancy and lactation.
Early detection of breast cancer in high-risk women based on longitudinal changes in serum-based proteins: the TESTBREAST study
Sophie C. Hagenaars,B. Ravesteijn,Laura Dekker,L. Verhoeff,J.W. Aalberts,Elma Meershoek-Klein Kranenbarg,J. de Vries,Arjen J Witkamp,K. Schenk,Kbmi Keymeulen,Marian B. E. Menke-Pluijmers,A.E. Dassen,Birgitta Kortmann,E.J.T. Rutgers,C.M. Cobbaert,Theo M. Luider,Wilma E. Mesker,R.A.E.M. Tollenaar +17 more
TL;DR: In this paper , a prospective, multicenter Dutch TESTBREAST study aims to identify a novel panel of blood-based protein biomarkers for early breast cancer detection for high-risk women using a relatively simple blood test to monitor biomarker levels.
Early detection of breast cancer in high-risk women based on longitudinal changes in serum-based proteins: the TESTBREAST study, an update
Sophie Hagenaars,B. Ravesteijn,Lennard Dekker,Fred Romijn,Ronald van Vlierberghe,L. Verhoeff,A.E. Dassen,Jakob de Vries,Marian Menke-Pluijmers,Karin Schenk,Kristien Keymeulen,Birgitta Kortmann,A. Witkamp,Emiel Rutgers,Yuri van der Burgt,Elma Meershoek-Klein Kranenbarg,Christa Cobbaert,Theo Luider,Wilma Mesker,R. Tollenaar +19 more