L. Rosén
Karolinska Institutet
16 Papers
382 Citations
L. Rosén is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Dopamine & Substantia nigra. The author has an hindex of 14, co-authored 16 publications.
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Papers
Mapping and computer assisted morphometry and microdensitometry of glucocorticoid receptor immunoreactive neurons and glial cells in the rat central nervous system
Antonio Cintra,Michele Zoli,L. Rosén,Luigi F. Agnati,Sam Okret,Ac Wikstrom,J-Å Gustafsson,Kjell Fuxe +7 more
TL;DR: The results emphasize that glucocorticoids may appropriately tune networks of different areas to obtain optimal integration and in this way improve survival of the animal under challenging conditions.
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Protective actions of human recombinant basic fibroblast growth factor on MPTP-lesioned nigrostriatal dopamine neurons after intraventricular infusion
Gerson Chadi,A. Mø er,L. Rosén,Ann Marie Janson,L. A. Agnati,Menek Goldstein,Sven-Ove Ögren,Ralf F. Pettersson,Kjell Fuxe +8 more
TL;DR: Results indicate that hrFGF-2, directly and/or indirectly via astroglia, upon i.v.t. infusion exerts trophic effects on the nigrostriatal DA system and may increase survival of nigrostRIatal DA nerve cells exposed to the MPTP neurotoxin.
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Involvement of local ischemia in endothelin-1 induced lesions of the neostriatum of the anaesthetized rat
Kjell Fuxe,N. Kurosawa,Antonio Cintra,Åse Hallström,Michel Goiny,L. Rosén,L. F. Agnati,Urban Ungerstedt +7 more
TL;DR: The results indicate that ET-1 injected in the neostriatum may produce lesions by causing local ischemia, related to its vasoconstrictor activity and possibly also to an activation ofET-1 receptors in the astroglial-endothelial complex.
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Corticosterone increases FGF-2 (bFGF) immunoreactivity in the substantia nigra of the rat
TL;DR: The effects of acute and subchronic administrations of the adrenocortical hormone corticosterone on basic fibroblast growth factor (bFGF, FGF-2) immunoreactivity were studied in the substantia nigra of the rat by semiquantitative immunocytochemistry coupled with image analysis.
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Evidence for a protective action of the vigilance promoting drug modafinil on the MPTP-induced degeneration of the nigrostriatal dopamine neurons in the black mouse: an immunocytochemical and biochemical analysis.
Kjell Fuxe,Ann Marie Janson,L. Rosén,Ulla-Britt Finnman,Sergio Tanganelli,Michele Morari,Menek Goldstein,L. F. Agnati +7 more
TL;DR: In this paper, the ability of Modafinil to counteract 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-(MPTP)-induced degeneration of the nigrostriatal dopamine (DA) neurons of the black mouse was studied.
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