L. Gold
7 Papers
L. Gold is an academic researcher. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 2, co-authored 5 publications.
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Papers
18 kDa translocator protein positron emission tomography facilitates early and robust tumor detection in the immunocompetent SB28 glioblastoma mouse model
L. Bartos,S V Kirchleitner,Jens Blobner,Karin Wind,L. Kunze,Adrien Holzgreve,L. Gold,A.V Zatcepin,Z. I. Kolabas,Selin Ulukaya,Lorraine Weidner,S. Quach,Denise Messerer,Peter Bartenstein,Jörg C. Tonn,Markus J. Riemenschneider,Sibylle Ziegler,Louisa von Baumgarten,Nathalie L. Albert,Matthias Brendel +19 more
TL;DR: TSPO-PET imaging of immunocompetent SB28 mice facilitates early detection of tumor signals over sham lesions and could serve as a valuable translational model to study TSPO as an imaging biomarker.
Longitudinal [18F]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model
Adrien Holzgreve,D. Pötter,Matthias Brendel,Michael Orth,Lorraine Weidner,L. Gold,Maximilian A. Kirchner,L. Bartos,L. Unterrainer,Marcus Unterrainer,Katja Steiger,Louisa von Baumgarten,Maximilian Niyazi,Claus Belka,Peter Bartenstein,Markus J. Riemenschneider,Kirsten Lauber,Nathalie L. Albert +17 more
TL;DR: GE-180 PET imaging facilitates non-invasive in vivo monitoring of TSPO expression in the GL261 GBM mouse model and shows highly congruent tracer distribution, enabling straightforward identification of suitable models and scan time-points on previously generated tissue sections.
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution
L. Bartos,S V Kirchleitner,Z. I. Kolabas,S. Quach,Jens Blobner,Stephan A Mueller,Selin Ulukaya,Luciano Hoeher,Izabela Horvath,Karin Wind-Mark,Adrien Holzgreve,Viktoria Ruf,L. Gold,L. Kunze,Sebastian T Kunte,Philipp Beumers,M. Antons,A.V Zatcepin,Nils Briel,Leonie Hoermann,Denise Messerer,Peter Bartenstein,Markus J. Riemenschneider,Simon Lindner,Sibylle Ziegler,Jochen Herms,Stefan F. Lichtenthaler,Ali Ertürk,Jörg C. Tonn,Louisa von Baumgarten,Nathalie L. Albert,Matthias Brendel +31 more
TL;DR: In this paper , the authors developed immunomagnetic cell sorting after in vivo radiotracer injection (scRadiotracing) in combination with 3D-histology via tissue clearing to dissect the cellular allocation of PET signals in the tumor microenvironment.
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Identification of Activating Mutations in the Transmembrane and Extracellular Domains of EGFR
Anja Wagner,Edgar Galicia-Andrés,Magdalena Teufl,L. Gold,Christian Obinger,Peter Sykacek,Chris Oostenbrink,Michael W. Traxlmayr +7 more
TL;DR: This study demonstrates that unbiased screening for activating mutations in EGFR not only yields well-established substitutions located in the kinase domain but also activates mutations in other regions of EGFR, including the extracellular and transmembrane domains.
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The amino acid stress sensing eIF2α kinase GCN2 is a survival biomarker for malignant mesothelioma
TL;DR: In this paper , the authors measured the levels of General Control Non-derepressible 2 (GCN2) protein in malignant mesothelioma tumour samples and determined whether these levels correlate with clinical outcomes.