L. E. Maxwell
Australian National University
2 Papers
111 Citations
L. E. Maxwell is an academic researcher from Australian National University. The author has contributed to research in topics: Plasmodium vinckei & Haemolysis. The author has an hindex of 2, co-authored 2 publications.
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Papers
•Journal Article
Radical-mediated damage to parasites and erythrocytes in Plasmodium vinckei infected mice after injection of t-butyl hydroperoxide.
TL;DR: Injection of desferrioxamine prevented both parasite death and haemolysis and suggests that t-butyl hydroperoxide damaged parasites and erythrocytes by dissociating into radical species, rather than by decreasing intraERYthrocyte anti-oxidant capacity.
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Activity of divicine in Plasmodium vinckei‐infected mice has implications for treatment of favism and epidemiology of G‐6‐PD deficiency
TL;DR: These observations support the hypothesis advanced by Huheey & Martin to explain the patchy geographical distribution of glucose‐6‐phosphate dehydrogenase deficiency in historic malarial areas and suggest that desferrioxamine, a drug already in clinical use, is a potential treatment for favism and other examples of oxidative haemolysis.
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