Kyung Sang Yu
New Generation University College
306 Papers
1.3K Citations
Kyung Sang Yu is an academic researcher from New Generation University College. The author has contributed to research in topics: Pharmacokinetics & Medicine. The author has an hindex of 30, co-authored 271 publications. Previous affiliations of Kyung Sang Yu include Seoul National University Hospital.
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Papers
Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers
Jae Yong Chung,Joo Youn Cho,Kyung Sang Yu,Jung-Ryul Kim,Dal-Seok Oh,Hye-Ryung Jung,Kyoung-Soo Lim,Ki-Ho Moon,Sang-Goo Shin,In-Jin Jang +9 more
TL;DR: The effects of organic anion transporting polypeptide 1B1 alleles *1a, *1b, and *15 on the pharmacokinetics of pitavastatin are characterized.
177
Pharmacokinetics and Tolerance of the Phage Endolysin-Based Candidate Drug SAL200 after a Single Intravenous Administration among Healthy Volunteers.
Soo Youn Jun,In-Jin Jang,Seonghae Yoon,Kyungho Jang,Kyung Sang Yu,Joo Youn Cho,Moon Woo Seong,Gi Mo Jung,Seong Jun Yoon,Sang Hyeon Kang +9 more
TL;DR: SAL200, a new candidate drug for the treatment of antibiotic-resistant staphylococcal infections based on a recombinant form of the phage endolysin SAL-1, was well tolerated, and no serious adverse events were observed in this clinical study.
148
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.
So-Young Yi,Kyoung-Sup Hong,Hyeong-Seok Lim,Jae Yong Chung,Dal-Seok Oh,Jung-Ryul Kim,Hye-Ryung Jung,Joo Youn Cho,Kyung Sang Yu,In-Jin Jang,Sang-Goo Shin +10 more
TL;DR: This study was performed to clarify the effects of major MDR1 gene polymorphisms, including a variant A allele in exon 21, on fexofenadine pharmacokinetics.
125
Identification of a quadruple mutation that confers tenofovir resistance in chronic hepatitis B patients
Eun Sook Park,Ah Ram Lee,Doo Hyun Kim,Jeong Hoon Lee,Jeong-Ju Yoo,Sung Hyun Ahn,Heewoo Sim,Soree Park,Hong Seok Kang,Juhee Won,Yea Na Ha,Gu Choul Shin,So Young Kwon,Yong Kwang Park,Byeong Sun Choi,Yun Bin Lee,Nakcheol Jeong,Yohan An,Young Seok Ju,Su Jong Yu,Hee Bok Chae,Kyung Sang Yu,Yoon Jun Kim,Jung Hwan Yoon,Fabien Zoulim,Kyun-Hwan Kim +25 more
TL;DR: The results demonstrate that tenofovir-resistant HBV mutants can emerge, although the genetic barrier is high, and reveal that the quadruple (CYEI) mutation increases the amount of ten ofovir required to inhibit HBV by 15.3-fold in IC50 and 26.3% in IC90.
122
Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states.
Kyung Sang Yu,Joo Youn Cho,In-Jin Jang,Kyoung-Seop Hong,Jae Yong Chung,Jung-Ryul Kim,Hyeong-Seok Lim,Dal-Seok Oh,So-Young Yi,Kwang-Hyeon Liu,Jae-Gook Shin,Sang-Goo Shin +11 more
TL;DR: The objective was to investigate the effect of the CYP3A5 genotype on the systemic clearance of midazolam in constitutive, inhibited, and induced metabolic conditions.
108