Kyu-Yong Lee
Hanyang University
80 Papers
307 Citations
Kyu-Yong Lee is an academic researcher from Hanyang University. The author has contributed to research in topics: Neuroprotection & Viability assay. The author has an hindex of 16, co-authored 75 publications.
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Papers
Effects of GV1001 on Language Dysfunction in Patients With Moderate-to-Severe Alzheimer’s Disease: Post Hoc Analysis of Severe Impairment Battery Subscales
Hyuk Sung Kwon,Seong-Ho Koh,Seong Hye Choi,Jee Hyang Jeong,Hae Ri Na,Chan Nyoung Lee,YoungSoon Yang,Ae-Young Lee,Jae-Hong Lee,Kyung-Won Park,Hyun Jeong Han,Byeong C. Kim,Jinse Park,J. Lee,Kyu-Yong Lee,Sangjae Kim +15 more
TL;DR: Patients with moderate-to-severe AD receiving GV1001 had greater language benefits than those receiving placebo, as measured using the SIB language subscale.
The novel vaccine peptide GV1001 effectively blocks β-amyloid toxicity by mimicking the extra-telomeric functions of human telomerase reverse transcriptase
Hyun-Hee Park,Kyu-Yong Lee,Sangjae Kim,Jessica Woojin Lee,Na-Young Choi,Eun-Hye Lee,Young Joo Lee,Sang Hun Lee,Seong-Ho Koh +8 more
TL;DR: It is suggested that GV1001 possesses neuroprotective effects against Aβ₂₅₋₃₁ oligomer in NSCs and that these effects are mediated through mimicking the extra-telomeric functions of human telomerase reverse transcriptase, including the induction of cellular proliferation, anti-apoptotic effects, mitochondrial stabilization, and anti-aging andAnti-oxidant effects.
Design and Rationale of the Intima-Medial Thickness Sub-Study of the PreventIon of CArdiovascular Events in iSchemic Stroke Patients with High Risk of Cerebral hemOrrhage (PICASSO-IMT) Study.
Woo-Keun Seo,Yong-Jae Kim,Juneyoung Lee,Juneyoung Lee,Sun U. Kwon,S. U. Kwon,Jong-Mun Lee,Yoon Jun Kim,W.K. Seo,Sang Hyub Lee,Yong Seok Lee,Dong-Eog Kim,Je-Sung Lee,Joung-Ho Rha,Kwang-Yeol Park,Sung Hyuk Heo,Kyung-Hwan Cho,Hahn-Young Kim,Yoonseung Kim,A-Hyun Cho,Jong Sam Baik,Jin Soo Lee,Juri Park,Tai-Hwan Park,Eung-Gyu Kim,Im Seok Koh,Jae-Kwan Cha,Nack Cheon Choi,J.H. Kwon,Sung Il Sohn,Jun Hong Lee,Y.H. Hwang,Hee-Jung Song,Byoung-Soo Shin,Joon-Tae Kim,Soo-Joo Lee,Hye-Ja Park,Sung Hwan Ahn,P.W. Chung,S.B. Kwon,D.I. Sin,Jin Kuk Do,Su-Hyeon Lee,Yeong-Bae Lee,B.G. Yoo,Sang-Min Sung,Ok Jun Kim,Jiyeon Jung,Kyu-Yong Lee,Yo Han Jung +49 more
TL;DR: PICASSO-IMT will provide the largest IMT data set in a stroke population and will provide valuable information about the clinical significance of IMT in patients with ischemic stroke.
The Role of Matrix Metalloproteinase 9 in Early Neurological Worsening of Acute Lacunar Infarction
Young Seo Kim,Kyu-Yong Lee,Seong-Ho Koh,Chang Yun Park,Hyun Young Kim,Young-Joo Lee,Hee Tae Kim,Juhan Kim,Myung-Ho Kim,Kyung Suk Kim,Dae-Il Chang,Seung Hyun Kim +11 more
TL;DR: It is suggested that the inflammatory process could play an important role in early neurological worsening of acute lacunar infarction.
GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects.
Hyun-Hee Park,Hyuk Sung Kwon,Kyu-Yong Lee,Ye Eun Kim,Jeongu Son,Na-Young Choi,Myung-Hoon Han,Dong Woo Park,Sangjae Kim,Seong-Ho Koh +9 more
TL;DR: It is suggested that GV1001 exerts anti-ageing effects in 3xTg-AD mice by reducing neurodegeneration and senescence, which contributes to improved survival.