Kyle Lapham
University of California, San Francisco
4 Papers
11 Citations
Kyle Lapham is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Throughput (business) & Population. The author has an hindex of 4, co-authored 4 publications.
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Papers
Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
Kyle Lapham,Mark N. Kvale,Jue Lin,Sheryl Connell,Lisa A. Croen,Brad Dispensa,Lynn Fang,Stephanie Hesselson,Thomas J. Hoffmann,Carlos Iribarren,Eric Jorgenson,Lawrence H. Kushi,Dana Ludwig,Tetsuya Matsuguchi,William B. McGuire,Sunita Miles,Charles P. Quesenberry,Sarah Rowell,Marianne Sadler,Lori C. Sakoda,David Smethurst,Carol P. Somkin,Stephen K. Van Den Eeden,Lawrence Walter,Rachel A. Whitmer,Pui-Yan Kwok,Neil Risch,Neil Risch,Catherine Schaefer,Elizabeth H. Blackburn +29 more
TL;DR: This study establishes reliable assay and analysis methodologies for measurement of TL in large, population-based human studies in the GERA cohort, the largest currently available such resource, linked to comprehensive electronic health and genotype data for analysis.
131
Patent
High-throughput sample processing systems and methods of use
Kyle Lapham,James Cregg,Daniel Delubac,Stuart Ira Glaser +3 more
- 02 Jun 2015
TL;DR: In this article, high-throughput sample processing systems and waste management systems, and methods of using the same are discussed. But they do not discuss the use of the same for the same.
11
B4-3: Demographic and Behavioral Influences on Telomere Length and Relationship with All-Cause Mortality: Early Results from the Kaiser Permanente Research Program on Genes, Environment, and Health (RPGEH)
Cathy Schaefer,Stan Sciortino,Mark N. Kvale,Kyle Lapham,Dilrini K. Ranatunga,Sarah Rowell,Marianne Sadler,Dana Ludwig,Lawrence Walter,Stephen K. Van Den Eeden,Rachel A. Whitmer +10 more
TL;DR: It was found that short TL was prospectively associated with mortality, although only those with the shortest TL were at increased risk; the association suggested a critical threshold of short TL determines effects on mortality.
Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study.
Ramin Farzaneh-Far,Jue Lin,Elissa S. Epel,Kyle Lapham,Elizabeth H. Blackburn,Mary A. Whooley,Mary A. Whooley +6 more
TL;DR: Leukocyte telomere length may increase as well as decrease in persons with coronary artery disease, possibly suggesting negative feedback regulation and the mechanisms and reversibility of telomeric aging in cardiovascular disease deserve further study.