Kyle C. Costa
University of Minnesota
27 Papers
21 Citations
Kyle C. Costa is an academic researcher from University of Minnesota. The author has contributed to research in topics: Methanococcus maripaludis & Methanogenesis. The author has an hindex of 13, co-authored 25 publications. Previous affiliations of Kyle C. Costa include California Institute of Technology & University of Washington.
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Papers
Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase
Kyle C. Costa,Phoebe M. Wong,Tiansong Wang,Thomas J. Lie,Jeremy A. Dodsworth,Jeremy A. Dodsworth,Ingrid Swanson,June A. Burn,Murray Hackett,John A. Leigh +9 more
TL;DR: A protein complex from the hydrogenotrophic methanogen, Methanococcus maripaludis, that contains heterodisulfide reductase, formylmethanofuran dehydrogenase, F420-nonreducing hydrogenase, and formate dehydrogensase is identified, establishing a physical basis for the electron-bifurcation model of energy conservation.
184
Microbiology and geochemistry of great boiling and mud hot springs in the United States Great Basin.
Kyle C. Costa,Jason B. Navarro,Everett L. Shock,Chuanlun Zhang,Debbie Soukup,Brian P. Hedlund +5 more
TL;DR: The most abundant archaeal phylotype was closely related to “Candidatus Nitrosocaldus yellowstonii”, suggesting a role for ammonia oxidation in primary production; however, few other phylotypes could be linked with energy calculations because phylotypes were either related to chemoorganotrophs or were unrelated to known organisms.
164
Essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis
TL;DR: It is found that Eha does not function stoichiometrically for methanogenesis, implying that electron bifurcation must operate in vivo, and a substoichiometric requirement for H2 suggests that its role is anaplerotic.
114
Effects of H2 and formate on growth yield and regulation of methanogenesis in Methanococcus maripaludis
TL;DR: During continuous culture of Methanococcus maripaludis under defined nutrient conditions, growth yields relative to methane production decreased markedly with either H2 excess or formate excess, suggesting that this phenomenon occurs independently of the storage of intracellular carbon or a transcriptional response to methanogenesis.
63
Enzymatic Degradation of Phenazines Can Generate Energy and Protect Sensitive Organisms from Toxicity
TL;DR: Several conserved genes that are important for the degradation of three Pseudomonas-derived phenazines are identified, suggesting that soil mycobacteria can catabolize phenazines and thereby protect other organisms against phenazine toxicity suggests that phenazine degradation may influence turnover in situ.
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