An implantable infusion pump possesses operational functionality that is, at least in part, controlled by software operating in two processor ICs which are configured to perform some different and some duplicate functions. The pump exchanges messages with an external device via telemetry. Each processor controls a different part of the drug infusion mechanism such that both processors must agree on the appropriateness of drug delivery for infusion to occur. Delivery accumulators are incremented and decremented with delivery requests and with deliveries made. When accumulated amounts reach or exceed, quantized deliverable amounts, infusion is made to occur. The accumulators are capable of being incremented by two or more independent types of delivery requests. Operational modes of the infusion device are changed automatically in view of various system errors that are trapped, various system alarm conditions that are detected, and when excess periods of time lapse between pump and external device interactions.

Microprocessor controlled ambulatory medical apparatus with hand held communication device

A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.

Ambulatory medical apparatus with hand held communication device

An implanted medical device (e.g. infusion pump) and external device communicate with one another via telemetry wherein messages are transmitted under a robust communication protocol. The communication protocol gives enhanced assurance concerning the integrity of messages that impact medical operations of the implantable device. Messages are transmitted using a multipart format that includes a preamble, a frame sync, a telemetry ID, data, and a validation code. The data portion of the message includes an op-code that dictates various other elements that form part of the message. The data portion may also include additional elements such as sequence numbers, bolus numbers, and duplicate data elements. A telemetry ID for the transmitting device may be implicitly embedded in the message as part of the validation code that is sent with the message and that must be pre-known by the receiver to confirm the integrity of the received message.

Ambulatory medical apparatus and method using a robust communication protocol

An implanted medical device (e.g. infusion pump) and an external device communicate with one another via telemetry messages that are receivable only during windows or listening periods. Each listening period is open for a prescribed period of time and is spaced from successive listening periods by an interval. The prescribed period of time is typically kept small to minimize power consumption. To increase likelihood of successful communication, the window may be forced to an open state, by use of an attention signal, in anticipation of an incoming message. To further minimize power consumption, it is desirable to minimize use of extended attention signals, which is accomplished by the transmitter maintaining an estimate of listening period start times and attempting to send messages only during listening periods. In the communication device, the estimate is updated as a result of information obtained with the reception of each message from the medical device.

Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods

An implanted medical device (e.g. infusion pump) and handheld communication device communicate with one another via telemetry wherein transmitted messages have enhanced numbers of and/or regularity of bit transitions to minimize the risk of synchronization loss between transmitted bits of data and received bits of data. Bit transitions for portions of messages may be enhanced by applying a pseudo-randomization scheme to those portions of messages that are transmitted in a way that allows the receiver to extract the original data from the received randomized data. Preferred randomization techniques modify (i.e. randomize) the data using a CRC value that is being accumulated while simultaneously causing the modified data to modify subsequent accumulation of the CRC itself. Upon reception, the reversal of data randomization occurs so that the intended message is appropriately received.

Method and apparatus for communicating between an ambulatory medical device and a control device via telemetry using randomized data

A wireless or wired communication system and method is provided including a transmitter and a receiver. A RF communication system in accordance with the present invention includes an apparatus and gain control method between RF receiver (803) and baseband modem (804) in case of a plurality of gain stages (830, 846, 862) inside a receiver (803). The gain of each stage (830, 846, 862) can be controlled by an integrated gain controller (828). The gain controller (828) monitors the signal level of each gain stage (830, 846, 862) to place its gain to optimal value. The gain control apparatus and method can be implemented in a digital AGC system. The gain controller (828) accepts a signal (826) implementing gain control and thus there is no stability issue. When distributed gain stages are present inside a related art receiver and separate gain control loops are used, stability issues can arise.

Automatic gain control method for highly integrated communication receiver

This paper describes an I/O scheme for use in a high-speed bus which eliminates setup and hold time requirements between clock and data by using an oversampling method. The I/O circuit uses a low jitter phase-locked loop (PLL) which suppresses the effect of supply noise. Measured results show peak-to-peak jitter of 150 ps and r.m.s. jitter of 15.7 ps on the clock line. Two experimental chips with 4-pin interface have been fabricated with a 0.6 /spl mu/m CMOS technology, which exhibits the bandwidth of 960 Mb/s per pin.

A 960-Mb/s/pin interface for skew-tolerant bus using low jitter PLL

This paper describes a CMOS serial link allowing fully duplexed 500 Mbaud serial data communication. The CMOS serial link is a robust and low-cost solution to high data rate requirements. A central charge pump PLL for generating multiphase clocks for oversampling is shared by several serial link channels. Fully duplexed serial data communication is realized in the bidirectional bridge by separating incoming data from the mixed signal on the cable end. The digital PLL accomplishes process-independent data recovery by using a low-ratio oversampling, a majority voting, and a parallel data recovery scheme. Mostly, digital approach could extend its bandwidth further with scaled CMOS technology. A single channel serial link and a charge pump PLL are integrated in a test chip using 1.2 /spl mu/m CMOS process technology. The test chip confirms upto 500 Mbaud unidirectional mode operation and 320 Mbaud fully duplexed mode operation with pseudo random data patterns. >

A CMOS serial link for fully duplexed data communication

A fully integrated CMOS frequency synthesizer for PCS- and cellular-CDMA systems is integrated in a 0.35-/spl mu/m CMOS technology. The proposed charge-averaging charge pump scheme suppresses fractional spurs to the level of noise, and the improved architecture of the dual-path loop filter makes it possible to implement a large time constant on a chip. With current-feedback bias and coarse tuning, a voltage-controlled oscillator (VCO) enables constant power and low gain of the VCO. Power dissipation is 60 mW with a 3.0-V supply. The proposed frequency synthesizer provides 10-kHz channel spacing with phase noise of -121 dBc/Hz in the PCS band and -127 dBc/Hz in the cellular band, both at 1-MHz offset frequency.

A fully integrated CMOS frequency synthesizer with charge-averaging charge pump and dual-path loop filter for PCS- and cellular-CDMA wireless systems

This paper presents a full-CMOS transmitter and receiver for 2.0-GHz wide-band code division multiple access with direct conversion mixers and a DC-offset cancellation scheme. The direct conversion scheme combined with a multiphase sampling fractional-N prescaler alleviates the problems of the direct conversion transmitter and receiver. Digital gain control is merged into the baseband filters and variable-gain amplifiers to optimize the linearity of the system, reduce the noise, and improve the sensitivity. Variable-gain amplifiers with DC-offset cancellation loop eliminate the DC-offset in each stage. The chip implemented in 0.35-/spl mu/m CMOS technology shows the experimental results of 6 dBm maximum output power with 38-dB adjacent channel power rejection ratio at 1.92 MHz, 50-dB dynamic range, and 363-mW power consumption in the transmitter. The receiver shows -115.4 dBm sensitivity, a 4.0-dB noise figure, and a dynamic range of 80-dB with 396-mW power consumption.

Full-CMOS 2-GHz WCDMA direct conversion transmitter and receiver

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